{"title":"肠神经系统中的PIEZO1维持肠道运转。","authors":"Britya Ghosh, Kara L Marshall","doi":"10.1016/j.neuron.2025.04.032","DOIUrl":null,"url":null,"abstract":"<p><p>Recently in Cell, Xie and Rose et al.<sup>1</sup> revealed a role for the mechanosensory ion channel PIEZO1 in the enteric nervous system, showing that it influences colonic motility and peristalsis, and highlighted its importance in the complex immuno-mechanical control of gastrointestinal function.</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 10","pages":"1466-1468"},"PeriodicalIF":14.7000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PIEZO1 in the enteric nervous system keeps the gut going.\",\"authors\":\"Britya Ghosh, Kara L Marshall\",\"doi\":\"10.1016/j.neuron.2025.04.032\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Recently in Cell, Xie and Rose et al.<sup>1</sup> revealed a role for the mechanosensory ion channel PIEZO1 in the enteric nervous system, showing that it influences colonic motility and peristalsis, and highlighted its importance in the complex immuno-mechanical control of gastrointestinal function.</p>\",\"PeriodicalId\":19313,\"journal\":{\"name\":\"Neuron\",\"volume\":\"113 10\",\"pages\":\"1466-1468\"},\"PeriodicalIF\":14.7000,\"publicationDate\":\"2025-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuron\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.neuron.2025.04.032\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.04.032","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
PIEZO1 in the enteric nervous system keeps the gut going.
Recently in Cell, Xie and Rose et al.1 revealed a role for the mechanosensory ion channel PIEZO1 in the enteric nervous system, showing that it influences colonic motility and peristalsis, and highlighted its importance in the complex immuno-mechanical control of gastrointestinal function.
期刊介绍:
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.