策划单细胞数据图谱，以更深入地了解肿瘤内异质性。

IF 28.5 1区医学 Q1 ONCOLOGY

Nature cancer Pub Date : 2025-05-22 DOI:10.1038/s43018-025-00956-9

引用次数: 0

摘要

我们建立了一个包含124个肿瘤单细胞rna测序数据集的数据库，并用它系统地表征肿瘤内的表达异质性。这些数据和分析共同构成了抗癌细胞图谱，并可通过增强的在线门户免费探索和下载。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Curating a single-cell data atlas for a deeper understanding of intra-tumor heterogeneity

查看原文本刊更多论文

Curating a single-cell data atlas for a deeper understanding of intra-tumor heterogeneity

We built a repository of 124 tumor single-cell RNA-sequencing datasets and used it to systematically characterize the expression heterogeneity within tumors. These data and analyses together constitute the Curated Cancer Cell Atlas and are freely available for exploration and download via an enhanced online portal.

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来源期刊

Nature cancer Medicine-Oncology

CiteScore

31.10

自引率

1.80%

发文量

129

期刊介绍： Cancer is a devastating disease responsible for millions of deaths worldwide. However, many of these deaths could be prevented with improved prevention and treatment strategies. To achieve this, it is crucial to focus on accurate diagnosis, effective treatment methods, and understanding the socioeconomic factors that influence cancer rates. Nature Cancer aims to serve as a unique platform for sharing the latest advancements in cancer research across various scientific fields, encompassing life sciences, physical sciences, applied sciences, and social sciences. The journal is particularly interested in fundamental research that enhances our understanding of tumor development and progression, as well as research that translates this knowledge into clinical applications through innovative diagnostic and therapeutic approaches. Additionally, Nature Cancer welcomes clinical studies that inform cancer diagnosis, treatment, and prevention, along with contributions exploring the societal impact of cancer on a global scale. In addition to publishing original research, Nature Cancer will feature Comments, Reviews, News & Views, Features, and Correspondence that hold significant value for the diverse field of cancer research.