原生地裂菌饥饿诱导细胞融合过程中减数分裂相关表达模式的研究。

IF 4.5 1区生物学 Q1 BIOLOGY

BMC Biology Pub Date : 2025-05-22 DOI:10.1186/s12915-025-02246-3

Shan Gao, Marcel Dominik Solbach, Jens Bast, Kenneth Dumack

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引用次数: 0

摘要

背景：单细胞真核生物被广泛认为是无性生殖。然而，最近的研究结果表明，减数分裂及其扩展（有时是隐性的）有性生殖可能存在于几乎所有真核生物谱系中。结果：我们研究了原生根菌Fisculla terrestris在饥饿诱导下的融合转录组反应。对差异表达基因（DEGs）的研究，特别是对减数分裂相关基因表达的研究表明，某些形式的减数分裂和重组可能发生在这些根茎中。结论：饥饿触发了地芽孢杆菌减数分裂相关基因的表达变化。然而，这些过程是否与有性生殖相结合仍有待研究。

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Meiosis-associated expression patterns during starvation-induced cell fusion in the protist Fisculla terrestris.

Background: Unicellular eukaryotes were widely considered to r eproduce without sex. However, recent findings suggest that meiosis, and by extension (sometimes cryptic) sexual reproduction, might be present in almost all eukaryotic lineages.

Results: Here, we investigate the transcriptomic response underlying starvation-induced fusion in the Rhizaria protist Fisculla terrestris. Investigations of differentially expressed genes (DEGs) with a particular focus on the expression of meiosis-associated genes suggest that some form of meiosis and recombination might occur in these Rhizaria.

Conclusions: We showed that starvation triggered changes in gene expression of meiosis-associated genes in F. terrestris. However, if these processes are coupled with sexual reproduction remains to be investigated.

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来源期刊

BMC Biology 生物-生物学

CiteScore

7.80

自引率

1.90%

发文量

260

审稿时长

3 months

期刊介绍： BMC Biology is a broad scope journal covering all areas of biology. Our content includes research articles, new methods and tools. BMC Biology also publishes reviews, Q&A, and commentaries.