{"title":"面部黄褐斑女性性功能障碍:一项病例对照研究","authors":"Serap Koran Karadogan, Bora Irer","doi":"10.1007/s00403-025-04273-0","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Melasma is a well-established reason of psychosocial problems as well as other dermatoses. Unlike common psychological morbidities, such as depression and anxiety, sexual dysfunction (SD) has been scarcely explored. We aimed to assess the occurrence of SD in melasma using a prospective case-control study.</p><h3>Methods</h3><p>Sexual function of melasma patients (Group I) and healthy controls (Group II) were compared using Female Sexual Function Index (FSFI). Severity of melasma was assessed using Modified Melasma and Area and Severity Index (mMASI). Age in both groups and severity in Group I were divided into subgroups. Possible effects of these variables on FSFI scores were analysed.</p><h3>Results</h3><p>109 (55 in Group I; 54 in Group II) patients were included. Median FSFI scores of Group I were significantly lower than Group II (27,3 vs. 29,4). Arousal, orgasm and satisfaction were significantly lower in Group I. Median total FSFI scores and percentage of SD were not influenced by age and severity of melasma. Patients with mild melasma had better lubrication results than patients with moderate and severe melasma. Pain/discomfort domain score was higher in patients with severe melasma.</p><h3>Conclusions</h3><p>Dermatologists should keep in mind that melasma, particularly on face, as well as other dermatoses, may also impair the females’ self-esteem and relationships, thereby affect sexual well-being and these patients should be evaluated in a multidisciplinary approach, if necessary. We think our study highlights the need for a more detailed approach to the further studies of SD in females with melasma.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sexual dysfunction in women with facial melasma: a case control study\",\"authors\":\"Serap Koran Karadogan, Bora Irer\",\"doi\":\"10.1007/s00403-025-04273-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Melasma is a well-established reason of psychosocial problems as well as other dermatoses. Unlike common psychological morbidities, such as depression and anxiety, sexual dysfunction (SD) has been scarcely explored. We aimed to assess the occurrence of SD in melasma using a prospective case-control study.</p><h3>Methods</h3><p>Sexual function of melasma patients (Group I) and healthy controls (Group II) were compared using Female Sexual Function Index (FSFI). Severity of melasma was assessed using Modified Melasma and Area and Severity Index (mMASI). Age in both groups and severity in Group I were divided into subgroups. Possible effects of these variables on FSFI scores were analysed.</p><h3>Results</h3><p>109 (55 in Group I; 54 in Group II) patients were included. Median FSFI scores of Group I were significantly lower than Group II (27,3 vs. 29,4). Arousal, orgasm and satisfaction were significantly lower in Group I. Median total FSFI scores and percentage of SD were not influenced by age and severity of melasma. Patients with mild melasma had better lubrication results than patients with moderate and severe melasma. Pain/discomfort domain score was higher in patients with severe melasma.</p><h3>Conclusions</h3><p>Dermatologists should keep in mind that melasma, particularly on face, as well as other dermatoses, may also impair the females’ self-esteem and relationships, thereby affect sexual well-being and these patients should be evaluated in a multidisciplinary approach, if necessary. We think our study highlights the need for a more detailed approach to the further studies of SD in females with melasma.</p></div>\",\"PeriodicalId\":8203,\"journal\":{\"name\":\"Archives of Dermatological Research\",\"volume\":\"317 1\",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-05-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Dermatological Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00403-025-04273-0\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Dermatological Research","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00403-025-04273-0","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
黄褐斑是一个公认的社会心理问题以及其他皮肤病的原因。与常见的心理疾病,如抑郁和焦虑不同,性功能障碍(SD)很少被研究。我们旨在通过一项前瞻性病例对照研究来评估黄褐斑中SD的发生情况。方法采用女性性功能指数(FSFI)对黄褐斑患者(I组)和健康对照组(II组)的性功能进行比较。采用改良黄褐斑面积及严重程度指数(mMASI)评价黄褐斑的严重程度。两组患者的年龄和第一组患者的严重程度分为亚组。分析了这些变量对FSFI评分的可能影响。结果1组109例(55例);II组54例。I组FSFI评分中位数明显低于II组(27.3 vs. 29.4)。性唤起、性高潮和满意度显著低于第一组。FSFI总分中位数和SD百分比不受年龄和黄褐斑严重程度的影响。轻度黄褐斑患者润滑效果优于中度和重度黄褐斑患者。重度黄褐斑患者疼痛/不适域评分较高。结论皮肤科医生应牢记,黄褐斑,特别是面部黄褐斑,以及其他皮肤病,也可能损害女性的自尊和人际关系,从而影响性健康,必要时应采用多学科方法对这些患者进行评估。我们认为我们的研究强调需要更详细的方法来进一步研究女性黄褐斑的SD。
Sexual dysfunction in women with facial melasma: a case control study
Background
Melasma is a well-established reason of psychosocial problems as well as other dermatoses. Unlike common psychological morbidities, such as depression and anxiety, sexual dysfunction (SD) has been scarcely explored. We aimed to assess the occurrence of SD in melasma using a prospective case-control study.
Methods
Sexual function of melasma patients (Group I) and healthy controls (Group II) were compared using Female Sexual Function Index (FSFI). Severity of melasma was assessed using Modified Melasma and Area and Severity Index (mMASI). Age in both groups and severity in Group I were divided into subgroups. Possible effects of these variables on FSFI scores were analysed.
Results
109 (55 in Group I; 54 in Group II) patients were included. Median FSFI scores of Group I were significantly lower than Group II (27,3 vs. 29,4). Arousal, orgasm and satisfaction were significantly lower in Group I. Median total FSFI scores and percentage of SD were not influenced by age and severity of melasma. Patients with mild melasma had better lubrication results than patients with moderate and severe melasma. Pain/discomfort domain score was higher in patients with severe melasma.
Conclusions
Dermatologists should keep in mind that melasma, particularly on face, as well as other dermatoses, may also impair the females’ self-esteem and relationships, thereby affect sexual well-being and these patients should be evaluated in a multidisciplinary approach, if necessary. We think our study highlights the need for a more detailed approach to the further studies of SD in females with melasma.
期刊介绍:
Archives of Dermatological Research is a highly rated international journal that publishes original contributions in the field of experimental dermatology, including papers on biochemistry, morphology and immunology of the skin. The journal is among the few not related to dermatological associations or belonging to respective societies which guarantees complete independence. This English-language journal also offers a platform for review articles in areas of interest for dermatologists and for publication of innovative clinical trials.