在放射治疗创新过程中支持决策的探索性健康经济分析:磁共振线性加速器为案例研究

Q1 Nursing
Marike J. Ulehake , Ellen J.L. Brunenberg , Marcel Verheij , Janneke P.C. Grutters
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引用次数: 0

摘要

背景和目的在放射治疗创新被广泛采用之前,人们越来越需要了解其附加价值。对于多用途创新,如磁共振直线加速器(MR-Linac),确定其在特定临床环境中的价值并不能最终回答创新是否证明所需投资是合理的这个更广泛的问题。探索性分析可以在创新的早期开发和使用中提供信息。我们的目标是开发和展示一个在线的、灵活的工具,以促进对linac先生的早期经济评估。材料和方法我们开发了一种工具,使用户能够通过输入特定于其背景的数据来比较mri引导放射治疗(MRIgRT)与常规治疗所需的总成本和增量效果。该工具包含的费用包括医疗技术和人员相关费用。需要证明潜在额外费用的效果用质量调整生命年(QALYs)表示。默认情况下,输入值是根据荷兰临床环境定制的。当用户输入特定于其背景或情况的数据时,该工具会生成显示MRIgRT与常规治疗相比(额外)成本和效果的数字。这些数字使用户能够探索关键变量对(额外)成本和qaly的影响,以证明与MRIgRT相关的任何潜在额外成本是合理的。结论该工具及其附带的示例允许探索性早期HTA分析,这可以为MRIgRT的成本效益提供见解。这些见解对于指导有关购买和使用创新放射治疗技术的决策是有价值的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploratory health economic analyses to support decisions within the innovation process in radiotherapy: Magnetic Resonance Linear Accelerator as a case study

Background and purpose

There is an increasing need for understanding the added value of radiotherapeutic innovations before their widespread adoption. For multi-purpose innovations such as the Magnetic Resonance Linear Accelerator (MR-Linac), determining their value within a specific clinical context does not conclusively answer the broader question whether the innovation justifies the required investment. Exploratory analyses can be informative during early development and use of the innovation. We aim to develop and demonstrate an online, flexible tool to facilitate early economic evaluation of the MR-Linac.

Materials and methods

We developed a tool that enables users to compare the total costs and incremental effects needed of MRI-guided radiotherapy (MRIgRT) with conventional treatment by inputting data specific to their context. Costs included in the tool are both medical technology and personnel-related expenses. The effects, required to justify potential additional costs, are expressed in Quality Adjusted Life Years (QALYs). By default, input values are used tailored to the Dutch clinical context.

Results

When users input data specific to their context or situation, the tool generates figures that display the (additional) costs and effects of MRIgRT compared to conventional treatment. These figures enable users to explore the impact of key variables on the (additional) costs and QALYs required to justify any potential extra costs associated with MRIgRT.

Conclusion

The tool and accompanying example allow for exploratory early HTA analyses, which can offer insights into the cost-effectiveness of MRIgRT. These insights can be valuable for guiding decisions regarding the purchase and utilization of innovative radiotherapeutic technologies.
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
48
审稿时长
67 days
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