芬兰微量元素的非职业暴露——尿液和血液生物监测研究

Q2 Environmental Science
Simo P. Porras, Juha Tuovila, Tiina Santonen
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引用次数: 0

摘要

本研究的目的是评估芬兰非职业、非吸烟、劳动年龄人群的微量元素暴露情况,并为这些微量元素在尿液和血液中的含量提供参考值。尿样分析了30种微量元素,血样分析了8种微量元素。这些样本是在2020年进行的。在147份尿样中,大多数所研究的微量元素是可量化的;只有铟和铱的结果低于定量限制。143份血样中微量元素均可定量测定。尿液中4种微量元素和血液中5种微量元素的测定结果男女差异有统计学意义。在大多数情况下,女性的暴露程度高于男性。仅在血铅和尿铜的结果中观察到年龄依赖性趋势。与其他国家的数据相比,芬兰的血铅水平较低,但尿砷和硒水平普遍较高。本研究结果将为职业健康工作提供参考值。我们强调,在设定参考值时,使用适当的参考人群来确定职业接触微量元素是很重要的。特别是在考虑降低职业接触极限值和相应的基于健康的微量元素生物极限值时,必须了解背景人群接触是不同的,以便正确解释来自职业接触人群的数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-occupational exposure to trace elements in Finland – Urinary and blood biomonitoring study
The aim of this study was to assess the exposure to trace elements of the non-occupationally exposed, non-smoking, working-age population in Finland, and to provide reference values for these trace elements in the urine and blood. Urine samples were analysed for 30 trace elements and blood samples for eight elements. The samplings took place in 2020.
In the urine samples (n = 147), most of the studied trace elements were quantifiable; only the indium and iridium results were below the limit of quantification. In the blood samples (n = 143), all the trace elements were quantifiable. The results regarding four trace elements in the urine and five trace elements in the blood were statistically different among the females to those among the males. In most cases, exposure was higher among the females than the males. An age-dependent trend was only observed in the results regarding lead in blood and copper in urine. In comparison to data from other countries, the blood lead levels were lower in Finland, but urinary arsenic and selenium levels were generally higher.
The results of this study will be used to set reference values for use in occupational health. We emphasize that it is important to use an appropriate reference population to identify occupational exposure to trace elements when setting reference values. Especially when considering a reduction in occupational exposure limit values and the corresponding health-based biological limit values for trace elements, it is essential to understand that the background population exposure varies to correctly interpret the data from occupationally exposed populations.
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来源期刊
Environmental Advances
Environmental Advances Environmental Science-Environmental Science (miscellaneous)
CiteScore
7.30
自引率
0.00%
发文量
165
审稿时长
12 weeks
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