Katayoun Rezaei, Marina Sánchez-Rico, Pierre Lavaud, Cécile Hanon, Emmanuel Leleu, Frédéric Limosin, Nicolas Hoertel
{"title":"老年人重度精神疾病的长期护理利用和全因死亡率:一项5年前瞻性多中心研究","authors":"Katayoun Rezaei, Marina Sánchez-Rico, Pierre Lavaud, Cécile Hanon, Emmanuel Leleu, Frédéric Limosin, Nicolas Hoertel","doi":"10.47626/1516-4446-2025-4114","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>As the population ages, the number of older adults with psychiatric disorders in long-term care facilities is expected to importantly increase. To our knowledge, no study to date has examined the association of long-term care utilization with all-cause mortality among older adults with psychiatric disorders.</p><p><strong>Methods: </strong>In this report, we used data from the \"Cohort of individuals with Schizophrenia, bipolar and major depressive disorder aged 55 years or more (CSA)\", a 5-year prospective multicenter study, to examine this association. All analyses were adjusted for a wide range of potential confounders, including sociodemographic and clinical characteristics, and psychotropic medication use.</p><p><strong>Results: </strong>The prevalence of long-term care utilization was 23.6% (n=132) among 559 older adults with major psychiatric disorders. Living in long-term care utilization was significantly and independently associated with increased all-cause mortality in both the crude (OR=2.54; 95%CI=1.67-3.87; p<0.001) and fully-adjusted multivariable logistic regression models (AOR=1.86; 95%CI=1.10-3.16; p=0.021). This association did not significantly vary across most subgroups defined by sociodemographic and clinical characteristics.</p><p><strong>Conclusions: </strong>In this multicenter prospective observational study of older adults with major psychiatric disorders, long-term care utilization was significantly associated with increased all-cause mortality. Physicians and policy makers should take this association under careful consideration.</p>","PeriodicalId":520767,"journal":{"name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Long-term Care Utilization and All-cause Mortality among Older Adults with Major Psychiatric Disorders: A 5-year Prospective Multicenter Study.\",\"authors\":\"Katayoun Rezaei, Marina Sánchez-Rico, Pierre Lavaud, Cécile Hanon, Emmanuel Leleu, Frédéric Limosin, Nicolas Hoertel\",\"doi\":\"10.47626/1516-4446-2025-4114\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>As the population ages, the number of older adults with psychiatric disorders in long-term care facilities is expected to importantly increase. To our knowledge, no study to date has examined the association of long-term care utilization with all-cause mortality among older adults with psychiatric disorders.</p><p><strong>Methods: </strong>In this report, we used data from the \\\"Cohort of individuals with Schizophrenia, bipolar and major depressive disorder aged 55 years or more (CSA)\\\", a 5-year prospective multicenter study, to examine this association. All analyses were adjusted for a wide range of potential confounders, including sociodemographic and clinical characteristics, and psychotropic medication use.</p><p><strong>Results: </strong>The prevalence of long-term care utilization was 23.6% (n=132) among 559 older adults with major psychiatric disorders. Living in long-term care utilization was significantly and independently associated with increased all-cause mortality in both the crude (OR=2.54; 95%CI=1.67-3.87; p<0.001) and fully-adjusted multivariable logistic regression models (AOR=1.86; 95%CI=1.10-3.16; p=0.021). This association did not significantly vary across most subgroups defined by sociodemographic and clinical characteristics.</p><p><strong>Conclusions: </strong>In this multicenter prospective observational study of older adults with major psychiatric disorders, long-term care utilization was significantly associated with increased all-cause mortality. Physicians and policy makers should take this association under careful consideration.</p>\",\"PeriodicalId\":520767,\"journal\":{\"name\":\"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47626/1516-4446-2025-4114\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47626/1516-4446-2025-4114","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Long-term Care Utilization and All-cause Mortality among Older Adults with Major Psychiatric Disorders: A 5-year Prospective Multicenter Study.
Objective: As the population ages, the number of older adults with psychiatric disorders in long-term care facilities is expected to importantly increase. To our knowledge, no study to date has examined the association of long-term care utilization with all-cause mortality among older adults with psychiatric disorders.
Methods: In this report, we used data from the "Cohort of individuals with Schizophrenia, bipolar and major depressive disorder aged 55 years or more (CSA)", a 5-year prospective multicenter study, to examine this association. All analyses were adjusted for a wide range of potential confounders, including sociodemographic and clinical characteristics, and psychotropic medication use.
Results: The prevalence of long-term care utilization was 23.6% (n=132) among 559 older adults with major psychiatric disorders. Living in long-term care utilization was significantly and independently associated with increased all-cause mortality in both the crude (OR=2.54; 95%CI=1.67-3.87; p<0.001) and fully-adjusted multivariable logistic regression models (AOR=1.86; 95%CI=1.10-3.16; p=0.021). This association did not significantly vary across most subgroups defined by sociodemographic and clinical characteristics.
Conclusions: In this multicenter prospective observational study of older adults with major psychiatric disorders, long-term care utilization was significantly associated with increased all-cause mortality. Physicians and policy makers should take this association under careful consideration.