Sunaina Khan, Alishba Zainab, Sapna Amin, Rashid Iqbal
{"title":"肝移植术后肺功能异常患者术后肺部并发症的发生率。","authors":"Sunaina Khan, Alishba Zainab, Sapna Amin, Rashid Iqbal","doi":"10.1177/03000605251340538","DOIUrl":null,"url":null,"abstract":"<p><p>ObjectiveTo determine the incidence of postoperative pulmonary complications in liver transplantation recipients with abnormal preoperative spirometry.MethodsA retrospective observational study was conducted among 210 patients with abnormal preoperative spirometry who underwent living donor liver transplantation between April 2012 and January 2024. Liver transplantation recipients were divided into two groups based on the spirometry diagnosis of restrictive lung disease or obstructive lung disease. The incidence of postoperative pulmonary complications and impact on patient outcomes were assessed in terms of length of stay in the intensive care unit, total length of stay in the hospital, time on the ventilator, duration of surgery, noninvasive ventilator dependence, reintubation rate, hospital-acquired infection, mortality, and arterial blood gas analysis.ResultsThe incidence of postoperative pulmonary complications was approximately 91.2% in liver transplantation recipients with abnormal preoperative spirometry. The length of stay in the intensive care unit, total length of stay in the hospital, duration of surgery, noninvasive ventilator dependence, reintubation rate, mortality, and hospital-acquired infections did not notably differ between recipients with restrictive lung disease (n = 189) and obstructive lung disease (n = 21).DiscussionAbnormal spirometry resulted in an increased incidence of postoperative pulmonary complications. However, the study suggests that the effects of abnormal spirometry were similar after liver transplantation.ConclusionPreexisting restrictive and obstructive lung diseases are associated with similar risks in liver transplantation recipients. However, as our study had fewer patients with obstructive lung disease, future research should include a comparable number of patients with restrictive and obstructive lung diseases to produce robust data on postoperative complications within this group for liver transplantation.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 5","pages":"3000605251340538"},"PeriodicalIF":1.4000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12099110/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence of postoperative pulmonary complications in recipients of liver transplantation with abnormal preoperative spirometry.\",\"authors\":\"Sunaina Khan, Alishba Zainab, Sapna Amin, Rashid Iqbal\",\"doi\":\"10.1177/03000605251340538\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>ObjectiveTo determine the incidence of postoperative pulmonary complications in liver transplantation recipients with abnormal preoperative spirometry.MethodsA retrospective observational study was conducted among 210 patients with abnormal preoperative spirometry who underwent living donor liver transplantation between April 2012 and January 2024. Liver transplantation recipients were divided into two groups based on the spirometry diagnosis of restrictive lung disease or obstructive lung disease. The incidence of postoperative pulmonary complications and impact on patient outcomes were assessed in terms of length of stay in the intensive care unit, total length of stay in the hospital, time on the ventilator, duration of surgery, noninvasive ventilator dependence, reintubation rate, hospital-acquired infection, mortality, and arterial blood gas analysis.ResultsThe incidence of postoperative pulmonary complications was approximately 91.2% in liver transplantation recipients with abnormal preoperative spirometry. The length of stay in the intensive care unit, total length of stay in the hospital, duration of surgery, noninvasive ventilator dependence, reintubation rate, mortality, and hospital-acquired infections did not notably differ between recipients with restrictive lung disease (n = 189) and obstructive lung disease (n = 21).DiscussionAbnormal spirometry resulted in an increased incidence of postoperative pulmonary complications. However, the study suggests that the effects of abnormal spirometry were similar after liver transplantation.ConclusionPreexisting restrictive and obstructive lung diseases are associated with similar risks in liver transplantation recipients. However, as our study had fewer patients with obstructive lung disease, future research should include a comparable number of patients with restrictive and obstructive lung diseases to produce robust data on postoperative complications within this group for liver transplantation.</p>\",\"PeriodicalId\":16129,\"journal\":{\"name\":\"Journal of International Medical Research\",\"volume\":\"53 5\",\"pages\":\"3000605251340538\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12099110/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of International Medical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/03000605251340538\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/22 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of International Medical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/03000605251340538","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/22 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Prevalence of postoperative pulmonary complications in recipients of liver transplantation with abnormal preoperative spirometry.
ObjectiveTo determine the incidence of postoperative pulmonary complications in liver transplantation recipients with abnormal preoperative spirometry.MethodsA retrospective observational study was conducted among 210 patients with abnormal preoperative spirometry who underwent living donor liver transplantation between April 2012 and January 2024. Liver transplantation recipients were divided into two groups based on the spirometry diagnosis of restrictive lung disease or obstructive lung disease. The incidence of postoperative pulmonary complications and impact on patient outcomes were assessed in terms of length of stay in the intensive care unit, total length of stay in the hospital, time on the ventilator, duration of surgery, noninvasive ventilator dependence, reintubation rate, hospital-acquired infection, mortality, and arterial blood gas analysis.ResultsThe incidence of postoperative pulmonary complications was approximately 91.2% in liver transplantation recipients with abnormal preoperative spirometry. The length of stay in the intensive care unit, total length of stay in the hospital, duration of surgery, noninvasive ventilator dependence, reintubation rate, mortality, and hospital-acquired infections did not notably differ between recipients with restrictive lung disease (n = 189) and obstructive lung disease (n = 21).DiscussionAbnormal spirometry resulted in an increased incidence of postoperative pulmonary complications. However, the study suggests that the effects of abnormal spirometry were similar after liver transplantation.ConclusionPreexisting restrictive and obstructive lung diseases are associated with similar risks in liver transplantation recipients. However, as our study had fewer patients with obstructive lung disease, future research should include a comparable number of patients with restrictive and obstructive lung diseases to produce robust data on postoperative complications within this group for liver transplantation.
期刊介绍:
_Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis.
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