类天疱疮妊娠与妊娠滋养细胞瘤相关：1例报告

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2025-05-20 DOI:10.1016/j.gore.2025.101771

Jasmine H. Wong , Udele Tagoe , Hatice B. Zengin , Bijal Amin , Beth N. McLellan , Matthew Cowan

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引用次数: 0

摘要

类天疱疮妊娠（PG）在妊娠中被很好地描述，典型的表现为在第二或第三个月的多胎妇女的瘙痒，脐周皮疹。我们描述了一个独特的情况下，一个妇女与妊娠滋养细胞瘤（GTN）状态后扩张和刮除甲氨蝶呤（MTX）谁提出了漫漫性，瘙痒皮疹。尽管多次使用甲氨蝶呤，但皮疹仍持续发作，活检支持PG的诊断。考虑PG与非妊娠GTN患者持续瘙痒性皮疹的区别是很重要的，即使在持续使用甲氨蝶呤治疗的情况下。

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Pemphigoid gestationis associated with gestational trophoblastic neoplasia: A case report

Pemphigoid gestationis (PG) is well described in pregnancy, classically presenting as a pruritic, periumbilical rash in multiparous women in the second or third trimester.

We describe a unique case of a woman with gestational trophoblastic neoplasia (GTN) status post dilation and curettage on methotrexate (MTX) who presented with a diffuse, pruritic rash. After the rash persisted and flared despite multiple cycles of MTX, biopsies were obtained supporting a diagnosis of PG.

It is important to consider PG on the differential in non-pregnant patients with GTN with a persistent pruritic rash, even in the setting of ongoing treatment with MTX.

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.