儿童和青少年血脂异常:当前的见解和最新的治疗方法。

IF 1.3 Q3 PEDIATRICS
Sung Eun Kim
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引用次数: 0

摘要

儿童和青少年中血脂异常发病率的增加已成为一个重大的公共卫生问题,因为它与长期心血管并发症的风险相关。血脂异常的患病率随着肥胖率的上升而增加,这突出了早期干预的重要性。在这篇叙述性综述中,我们探讨了儿科人群中血脂异常的流行病学、筛查、诊断和治疗,重点介绍了临床管理的最新进展和更新。讨论了关键的诊断标准和风险评估策略,强调了血脂筛查在高危人群中的作用。生活方式和饮食干预是控制血脂异常的关键,而包括他汀类药物、胆固醇吸收抑制剂和新兴疗法在内的药物治疗在需要进一步干预的情况下进行了回顾。本文综合了韩国和其他国际机构的最新指南和基于证据的建议,提供了全面的概述。这些发现强调了多学科结合早期检测、量身定制治疗和改变生活方式的必要性,以减轻与年轻人血脂异常相关的长期健康风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dyslipidemia in Children and Adolescents: Current Insights and Updated Treatment Approaches.

The increasing incidence of dyslipidemia among children and adolescents has emerged as a significant public health concern due to its associated risk of long-term cardiovascular complications. The prevalence of dyslipidemia has increased in parallel with rising obesity rates, highlighting the importance of early intervention. In this narrative review, we explore the epidemiology, screening, diagnosis, and treatment of dyslipidemia in pediatric populations, focusing on recent advancements and updates in clinical management. Key diagnostic criteria and risk assessment strategies are discussed, emphasizing the role of lipid profile screening in high-risk groups. Lifestyle and dietary interventions are key for managing dyslipidemia, while pharmacological treatments including statins, cholesterol absorption inhibitors, and emerging therapies are reviewed in cases requiring further intervention. Updated guidelines and evidence-based recommendations from Korean and other international institutions are consolidated to provide a comprehensive overview. These findings underscore the necessity of a multidisciplinary approach combining early detection, tailored treatment, and lifestyle modifications to mitigate the long-term health risks associated with dyslipidemia in younger individuals.

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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
43
期刊介绍: Pediatric Gastroenterology, Hepatology and Nutrition (Pediatr Gastroenterol Hepatol Nutr), an official journal of The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition, is issued bimonthly and published in English. The aim of Pediatr Gastroenterol Hepatol Nutr is to advance scientific knowledge and promote child healthcare by publishing high-quality empirical and theoretical studies and providing a recently updated knowledge to those practitioners and scholars in the field of pediatric gastroenterology, hepatology and nutrition. Pediatr Gastroenterol Hepatol Nutr publishes review articles, original articles, and case reports. All of the submitted papers are peer-reviewed. The journal covers basic and clinical researches on molecular and cellular biology, pathophysiology, epidemiology, diagnosis, and treatment of all aspects of pediatric gastrointestinal diseases and nutritional health problems.
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