肠道微生物组：温带和潜伏噬菌体在人类肠道中占主导地位。

IF 8.1 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Current Biology Pub Date : 2025-05-19 DOI:10.1016/j.cub.2025.01.006

Yan Huang, Teng Wang, Yingfei Ma

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引用次数: 0

摘要

大多数肠道细菌都是溶菌原，其中含有温带噬菌体，其诱导导致宿主裂解并破坏微生物群。最近的一篇论文结合数学模型来计算肠道中病毒与微生物的比例，并估计每天每个细菌的噬菌体诱导率约为0.001-0.01。这为人类肠道噬菌体的种群动态和生活方式特征提供了新的见解。

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Gut microbiome: Temperate and latent phages are dominant in the human gut.

Most gut bacteria are lysogens, harboring temperate phages whose induction leads to host lysis and disrupts the microbiome. A recent paper combines mathematical modeling to calculate the virus-to-microbe ratio in the gut and estimates a phage-induction rate of approximately 0.001-0.01 per bacterium per day. This provides new insights into the population dynamics and lifestyle characteristics of human gut phages.

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来源期刊

Current Biology 生物-生化与分子生物学

CiteScore

11.80

自引率

2.20%

发文量

869

审稿时长

46 days

期刊介绍： Current Biology is a comprehensive journal that showcases original research in various disciplines of biology. It provides a platform for scientists to disseminate their groundbreaking findings and promotes interdisciplinary communication. The journal publishes articles of general interest, encompassing diverse fields of biology. Moreover, it offers accessible editorial pieces that are specifically designed to enlighten non-specialist readers.