Asna Beg Ashraf, Meeta Meeta, A B Chitra, Sangeeta Pahwa, Jyoti Shah, Manjit Mohi, Geeta Reddy, Kiran Aggarwal, Amrita Sarkari, Sudha Sharma, Jyoti Jaiswal, Jignesh Shah, Bipasa Sen, Jyothi Unni, Sheela Mane, Jyothika Desai
{"title":"绝经期泌尿生殖系统综合征：一项来自印度中年登记处的多中心研究。","authors":"Asna Beg Ashraf, Meeta Meeta, A B Chitra, Sangeeta Pahwa, Jyoti Shah, Manjit Mohi, Geeta Reddy, Kiran Aggarwal, Amrita Sarkari, Sudha Sharma, Jyoti Jaiswal, Jignesh Shah, Bipasa Sen, Jyothi Unni, Sheela Mane, Jyothika Desai","doi":"10.1080/13697137.2025.2496681","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the prevalence and characteristics of genitourinary syndrome of menopause (GSM) in midlife women.</p><p><strong>Methods: </strong>The cross-sectional study from the Indian Midlife Registry included women aged >40 years attending outpatient clinics at multiple centers across India. Real-world data were collected on an Electronic Health Record platform. GSM was diagnosed in the presence of either two genitourinary or sexual symptoms or one symptom and a Vaginal Health Index (VHI) score of ≤15.</p><p><strong>Results: </strong>A total of 1781 women, 826 perimenopausal and 955 postmenopausal, were included. The prevalence of GSM was 48.5%, and the most prevalent symptoms were lower urinary tract symptoms (LUTS) (38.2%) and vaginal dryness (26.4%). The VHI score was ≤15 in 42.1% of women. Based on logistic regression analysis, age ≥70 years, late postmenopause, low education, insomnia and other sleep problems were associated with higher odds of GSM.</p><p><strong>Conclusion: </strong>GSM is highly prevalent in Indian women. GSM remains under-recognized and undertreated. Sleep problems, advanced age, late postmenopause and low education significantly increase the odds. This study underscores the importance of routine screening for GSM, especially in those with sleep disturbances or LUTS in order to improve quality of life (QoL).</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-8"},"PeriodicalIF":2.9000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Genitourinary syndrome of menopause: a multicenter study from the Indian Midlife Registry.\",\"authors\":\"Asna Beg Ashraf, Meeta Meeta, A B Chitra, Sangeeta Pahwa, Jyoti Shah, Manjit Mohi, Geeta Reddy, Kiran Aggarwal, Amrita Sarkari, Sudha Sharma, Jyoti Jaiswal, Jignesh Shah, Bipasa Sen, Jyothi Unni, Sheela Mane, Jyothika Desai\",\"doi\":\"10.1080/13697137.2025.2496681\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aimed to investigate the prevalence and characteristics of genitourinary syndrome of menopause (GSM) in midlife women.</p><p><strong>Methods: </strong>The cross-sectional study from the Indian Midlife Registry included women aged >40 years attending outpatient clinics at multiple centers across India. Real-world data were collected on an Electronic Health Record platform. GSM was diagnosed in the presence of either two genitourinary or sexual symptoms or one symptom and a Vaginal Health Index (VHI) score of ≤15.</p><p><strong>Results: </strong>A total of 1781 women, 826 perimenopausal and 955 postmenopausal, were included. The prevalence of GSM was 48.5%, and the most prevalent symptoms were lower urinary tract symptoms (LUTS) (38.2%) and vaginal dryness (26.4%). The VHI score was ≤15 in 42.1% of women. Based on logistic regression analysis, age ≥70 years, late postmenopause, low education, insomnia and other sleep problems were associated with higher odds of GSM.</p><p><strong>Conclusion: </strong>GSM is highly prevalent in Indian women. GSM remains under-recognized and undertreated. Sleep problems, advanced age, late postmenopause and low education significantly increase the odds. This study underscores the importance of routine screening for GSM, especially in those with sleep disturbances or LUTS in order to improve quality of life (QoL).</p>\",\"PeriodicalId\":10213,\"journal\":{\"name\":\"Climacteric\",\"volume\":\" \",\"pages\":\"1-8\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Climacteric\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/13697137.2025.2496681\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Climacteric","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/13697137.2025.2496681","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Genitourinary syndrome of menopause: a multicenter study from the Indian Midlife Registry.
Objective: This study aimed to investigate the prevalence and characteristics of genitourinary syndrome of menopause (GSM) in midlife women.
Methods: The cross-sectional study from the Indian Midlife Registry included women aged >40 years attending outpatient clinics at multiple centers across India. Real-world data were collected on an Electronic Health Record platform. GSM was diagnosed in the presence of either two genitourinary or sexual symptoms or one symptom and a Vaginal Health Index (VHI) score of ≤15.
Results: A total of 1781 women, 826 perimenopausal and 955 postmenopausal, were included. The prevalence of GSM was 48.5%, and the most prevalent symptoms were lower urinary tract symptoms (LUTS) (38.2%) and vaginal dryness (26.4%). The VHI score was ≤15 in 42.1% of women. Based on logistic regression analysis, age ≥70 years, late postmenopause, low education, insomnia and other sleep problems were associated with higher odds of GSM.
Conclusion: GSM is highly prevalent in Indian women. GSM remains under-recognized and undertreated. Sleep problems, advanced age, late postmenopause and low education significantly increase the odds. This study underscores the importance of routine screening for GSM, especially in those with sleep disturbances or LUTS in order to improve quality of life (QoL).
期刊介绍：
Climacteric is the official journal of the International Menopause Society (IMS). As an international peer-reviewed journal it publishes original research and reviews of all aspects of aging in women.
Climacteric was founded by the IMS in 1998 and today has become a leading journal in the publication of peer-reviewed papers on the menopause, climacteric and mid-life health. Topics covered include endocrine changes, symptoms attributed to the menopause and their treatment, hormone replacement and alternative therapies, lifestyles, and the counselling and education of peri- and postmenopausal women. Climacteric, published bimonthly, also features regular invited reviews, editorials and commentaries on recent developments.
The editorial review board of Climacteric includes leading scientific and clinical experts in the field of midlife medicine and research and is headed by its Editor-in-Chief, Professor Rod Baber of Australia. He and his team of Associate Editors act independently to set a clear editorial policy, co-ordinate peer review, and ensure a rapid response to submitted papers.
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