HELLP综合征和登革热孕妇的致命结局。

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Pierina A Garavito-Pérez, Joe C Olivares-López, Virgilio E Failoc-Rojas, Miguel A Vences
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引用次数: 0

摘要

溶血、肝酶升高和低血小板(HELLP)综合征是一种罕见的并发症,由妊娠高血压、溶血、肝酶升高和血小板减少症组成。登革热由虫媒病毒引起,表现为发热、血小板减少和出血性症状。我们报告一个26岁的孕妇在29周妊娠从秘鲁北部与先兆子痫。住院期间,她出现发热、血小板减少症,并通过非结构蛋白1抗原检测阳性诊断为严重登革热。她的病情恶化,因为先兆子痫的迹象严重。她被送进了重症监护室,并接受了剖腹产手术。在第7天,她出现了HELLP综合征和多器官衰竭,最终在第9天死亡。在流行地区,重要的是要考虑妊娠人群中可能同时出现高血压疾病和登革热的临床情况,因为及时诊断和适当管理这两种疾病是改善临床结果的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fatal Outcome in a Pregnant Woman with HELLP Syndrome and Dengue.

Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is a rare complication consisting of pregnancy-induced hypertension, hemolysis, elevated liver enzymes, and thrombocytopenia. Dengue, caused by an arbovirus, manifests with fever, thrombocytopenia, and hemorrhagic symptoms. We report a 26-year-old primigravida at 29 weeks of gestation from northern Peru with preeclampsia. During hospitalization, she developed fever, thrombocytopenia, and was diagnosed with severe dengue by a positive nonstructural protein 1 antigen test. Her condition worsened because of preeclampsia with signs of severity. She was admitted to the intensive care unit, and she did undergo a cesarean section. On the seventh day, she developed HELLP syndrome and multiple organ failure, culminating in her death on the ninth day. In endemic areas, it is important to consider clinical scenarios where the simultaneous manifestation of hypertensive disease and dengue may occur in the pregnant population, as timely diagnosis and appropriate management of both diseases are key to improve clinical outcomes.

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来源期刊
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.20
自引率
3.00%
发文量
508
审稿时长
3 months
期刊介绍: The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine. The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development. The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal. Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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