Pierina A Garavito-Pérez, Joe C Olivares-López, Virgilio E Failoc-Rojas, Miguel A Vences
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Fatal Outcome in a Pregnant Woman with HELLP Syndrome and Dengue.
Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is a rare complication consisting of pregnancy-induced hypertension, hemolysis, elevated liver enzymes, and thrombocytopenia. Dengue, caused by an arbovirus, manifests with fever, thrombocytopenia, and hemorrhagic symptoms. We report a 26-year-old primigravida at 29 weeks of gestation from northern Peru with preeclampsia. During hospitalization, she developed fever, thrombocytopenia, and was diagnosed with severe dengue by a positive nonstructural protein 1 antigen test. Her condition worsened because of preeclampsia with signs of severity. She was admitted to the intensive care unit, and she did undergo a cesarean section. On the seventh day, she developed HELLP syndrome and multiple organ failure, culminating in her death on the ninth day. In endemic areas, it is important to consider clinical scenarios where the simultaneous manifestation of hypertensive disease and dengue may occur in the pregnant population, as timely diagnosis and appropriate management of both diseases are key to improve clinical outcomes.
期刊介绍:
The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine.
The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development.
The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal.
Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries