腰椎减压手术中基于有限元的生物力学定量综述。

IF 3 3区 医学 Q2 BIOPHYSICS
Mary H Foltz, Alexandra H Seidenstein, Craig Almeida, Andrew Kim, Amit Jain, Jill M Middendorf
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引用次数: 0

摘要

在美国,腰椎减压手术通常用于治疗椎管狭窄引起的疼痛,通常很少甚至没有生物力学证据来评估给定手术的风险和益处。腰椎减压手术的有限元模型试图阐明这些手术的生物力学益处和风险。每个已发表的有限元模型都使用了腰椎减压手术的独特子集、独特的人类腰椎和独特的模型输入。因此,很难得出关于手术变异引起的生物力学变化和生物力学并发症的结论。本定量回顾分析了腰椎有限元模型中关于脊柱减压手术的应力、力和活动范围的报道。为了完成这一分析,将2000年至2023年12月发表的腰椎减压手术的有限元模型数据归一化到完整的脊柱并进行比较。该分析表明,与有限切除技术相比,骨切除和韧带切除的增加与病理活动范围的增加有关。此外,一些个体研究显示减压手术增加了IVD应力、关节间部应力和小关节受力等重要结果,但发表的模型数量少,限制了这些结果在普通人群中的推广。未来的有限元模型应该报告这些脊柱应力,并将患者特定的解剖学特征,如IVD健康状况、小关节面几何形状、患者椎骨狭窄和椎体孔隙度纳入模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A quantitative review of finite element-based biomechanics of lumbar decompression surgery.

Lumbar decompression surgeries are commonly performed in the USA to treat pain from spinal stenosis, often with little to no biomechanical evidence to evaluate the risks and benefits of a given surgery. Finite element models of lumbar spinal decompression surgeries attempt to elucidate the biomechanical benefits and risks of these procedures. Each published finite element model uses a unique subset of lumbar decompression surgeries, a unique human lumbar spine, and unique model inputs. Thus, drawing conclusions about biomechanical changes and biomechanical complications due to surgical variations is difficult. This quantitative review performed an analysis on the stresses, forces, and range of motion reported in lumbar spine finite element models that focus on spinal decompression surgeries. To accomplish this analysis, data from finite elements models of lumbar decompression surgeries published between 2000 and December 2023 were normalized to the intact spine and compared. This analysis indicated that increased bony resection and increased ligament resection are associated with increased pathologic range of motion compared to limited resection techniques. Further, a few individual studies show an increase in important outcomes such IVD stresses, pars interarticularis stresses, and facet joint forces due to decompression surgery, but the small number of published models with these results limits the generalizability of these findings to the general population. Future FE models should report these spinal stresses and incorporate patient-specific anatomical features such as IVD health, facet geometry, stenosis patient vertebrae, and vertebral porosity into the model.

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来源期刊
Biomechanics and Modeling in Mechanobiology
Biomechanics and Modeling in Mechanobiology 工程技术-工程:生物医学
CiteScore
7.10
自引率
8.60%
发文量
119
审稿时长
6 months
期刊介绍: Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. A goal of this journal is to promote basic and applied research that integrates the expanding knowledge-bases in the allied fields of biomechanics and mechanobiology. Approaches may be experimental, theoretical, or computational; they may address phenomena at the nano, micro, or macrolevels. Of particular interest are investigations that (1) quantify the mechanical environment in which cells and matrix function in health, disease, or injury, (2) identify and quantify mechanosensitive responses and their mechanisms, (3) detail inter-relations between mechanics and biological processes such as growth, remodeling, adaptation, and repair, and (4) report discoveries that advance therapeutic and diagnostic procedures. Especially encouraged are analytical and computational models based on solid mechanics, fluid mechanics, or thermomechanics, and their interactions; also encouraged are reports of new experimental methods that expand measurement capabilities and new mathematical methods that facilitate analysis.
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