Mengze Guo, Pingping Sun, Xudong Fan, Jianwei Guo, Lei Zhang, Zhengnan Li
{"title":"小叶榕相关病毒的全基因组序列和基因组组织——一种被推测为小叶榕科新成员的病毒","authors":"Mengze Guo, Pingping Sun, Xudong Fan, Jianwei Guo, Lei Zhang, Zhengnan Li","doi":"10.1007/s00705-025-06312-7","DOIUrl":null,"url":null,"abstract":"<div><p><i>Ficus pumila</i> is an edible garden plant with significant medicinal value. In this study, we identified a novel maculavirus associated with mosaic and chlorotic spot symptoms on <i>F. pumila</i> leaves in Yunnan Province, China, and the genome sequence of the virus, which was tentatively named \"Ficus pumila-associated virus\" (FPaV), was determined. The FPaV genome consists of a single molecule of positive-sense ssRNA that is 6,664 nucleotides in length and has a high cytidine content of 40.8%. The genome exhibits a tymovirus-like organization, encoding a movement protein (MP), a replicase polyprotein, and a coat protein (CP). Phylogenetic analysis showed FPaV to be most closely related to grapevine fleck virus (GFkV), with 67.86% nucleotide sequence identity across the complete genome.</p></div>","PeriodicalId":8359,"journal":{"name":"Archives of Virology","volume":"170 6","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Complete genome sequence and genome organization of Ficus pumila-associated virus, a new putative member of the family Tymoviridae\",\"authors\":\"Mengze Guo, Pingping Sun, Xudong Fan, Jianwei Guo, Lei Zhang, Zhengnan Li\",\"doi\":\"10.1007/s00705-025-06312-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><i>Ficus pumila</i> is an edible garden plant with significant medicinal value. In this study, we identified a novel maculavirus associated with mosaic and chlorotic spot symptoms on <i>F. pumila</i> leaves in Yunnan Province, China, and the genome sequence of the virus, which was tentatively named \\\"Ficus pumila-associated virus\\\" (FPaV), was determined. The FPaV genome consists of a single molecule of positive-sense ssRNA that is 6,664 nucleotides in length and has a high cytidine content of 40.8%. The genome exhibits a tymovirus-like organization, encoding a movement protein (MP), a replicase polyprotein, and a coat protein (CP). Phylogenetic analysis showed FPaV to be most closely related to grapevine fleck virus (GFkV), with 67.86% nucleotide sequence identity across the complete genome.</p></div>\",\"PeriodicalId\":8359,\"journal\":{\"name\":\"Archives of Virology\",\"volume\":\"170 6\",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Virology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00705-025-06312-7\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VIROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Virology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00705-025-06312-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}
Complete genome sequence and genome organization of Ficus pumila-associated virus, a new putative member of the family Tymoviridae
Ficus pumila is an edible garden plant with significant medicinal value. In this study, we identified a novel maculavirus associated with mosaic and chlorotic spot symptoms on F. pumila leaves in Yunnan Province, China, and the genome sequence of the virus, which was tentatively named "Ficus pumila-associated virus" (FPaV), was determined. The FPaV genome consists of a single molecule of positive-sense ssRNA that is 6,664 nucleotides in length and has a high cytidine content of 40.8%. The genome exhibits a tymovirus-like organization, encoding a movement protein (MP), a replicase polyprotein, and a coat protein (CP). Phylogenetic analysis showed FPaV to be most closely related to grapevine fleck virus (GFkV), with 67.86% nucleotide sequence identity across the complete genome.
期刊介绍：
Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.
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