Aqib Rahman, Nuzhat Jamil, Muhammad Yasir, Muhammad Nauman Aftab, Qudsia Kanwal, Muhammad Zubair Kamran, Ali Abbas Aslam, Muhammad Zaeem Mehdi, Hamda Akhtar, Mahmood Ahmed
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In addition, the article examines the mechanisms of nanomaterial toxicity and their effects on biological systems, highlighting the importance of interdisciplinary collaboration in developing effective risk assessment and management strategies and policies for NMs in the environment. The review also discusses NMs’ current regulatory and policy implications and suggests future research directions to enhance our understanding of the risks associated with these materials. It highlights the need for continued research on the toxicity of NMs in the environment and the development of effective risk assessment and management strategies and policies. The potential risks associated with NMs in the environment warrant careful consideration, and it is important to continue to monitor their effects on human health and the environment.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 6","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Toxicity of nanomaterials in the environment: a critical review of current understanding and future directions\",\"authors\":\"Aqib Rahman, Nuzhat Jamil, Muhammad Yasir, Muhammad Nauman Aftab, Qudsia Kanwal, Muhammad Zubair Kamran, Ali Abbas Aslam, Muhammad Zaeem Mehdi, Hamda Akhtar, Mahmood Ahmed\",\"doi\":\"10.1007/s11051-025-06345-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Nanomaterials (NMs) have unique properties, including high surface area, high reactivity, and quantum confinement effects, improving performance and new applications. This review article critically evaluates the current state of knowledge on the toxicity of NMs in the environment. It provides an overview of NMs and their sources and discusses the potential toxicity of different NMs in different environmental matrices. The review also explores the various factors that can influence the toxicity of NMs, including their size, shape, surface chemistry, concentration, dose, duration and frequency of exposure, and interaction with other pollutants. In addition, the article examines the mechanisms of nanomaterial toxicity and their effects on biological systems, highlighting the importance of interdisciplinary collaboration in developing effective risk assessment and management strategies and policies for NMs in the environment. The review also discusses NMs’ current regulatory and policy implications and suggests future research directions to enhance our understanding of the risks associated with these materials. It highlights the need for continued research on the toxicity of NMs in the environment and the development of effective risk assessment and management strategies and policies. The potential risks associated with NMs in the environment warrant careful consideration, and it is important to continue to monitor their effects on human health and the environment.</p></div>\",\"PeriodicalId\":653,\"journal\":{\"name\":\"Journal of Nanoparticle Research\",\"volume\":\"27 6\",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nanoparticle Research\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11051-025-06345-8\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nanoparticle Research","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1007/s11051-025-06345-8","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Toxicity of nanomaterials in the environment: a critical review of current understanding and future directions
Nanomaterials (NMs) have unique properties, including high surface area, high reactivity, and quantum confinement effects, improving performance and new applications. This review article critically evaluates the current state of knowledge on the toxicity of NMs in the environment. It provides an overview of NMs and their sources and discusses the potential toxicity of different NMs in different environmental matrices. The review also explores the various factors that can influence the toxicity of NMs, including their size, shape, surface chemistry, concentration, dose, duration and frequency of exposure, and interaction with other pollutants. In addition, the article examines the mechanisms of nanomaterial toxicity and their effects on biological systems, highlighting the importance of interdisciplinary collaboration in developing effective risk assessment and management strategies and policies for NMs in the environment. The review also discusses NMs’ current regulatory and policy implications and suggests future research directions to enhance our understanding of the risks associated with these materials. It highlights the need for continued research on the toxicity of NMs in the environment and the development of effective risk assessment and management strategies and policies. The potential risks associated with NMs in the environment warrant careful consideration, and it is important to continue to monitor their effects on human health and the environment.
期刊介绍:
The objective of the Journal of Nanoparticle Research is to disseminate knowledge of the physical, chemical and biological phenomena and processes in structures that have at least one lengthscale ranging from molecular to approximately 100 nm (or submicron in some situations), and exhibit improved and novel properties that are a direct result of their small size.
Nanoparticle research is a key component of nanoscience, nanoengineering and nanotechnology.
The focus of the Journal is on the specific concepts, properties, phenomena, and processes related to particles, tubes, layers, macromolecules, clusters and other finite structures of the nanoscale size range. Synthesis, assembly, transport, reactivity, and stability of such structures are considered. Development of in-situ and ex-situ instrumentation for characterization of nanoparticles and their interfaces should be based on new principles for probing properties and phenomena not well understood at the nanometer scale. Modeling and simulation may include atom-based quantum mechanics; molecular dynamics; single-particle, multi-body and continuum based models; fractals; other methods suitable for modeling particle synthesis, assembling and interaction processes. Realization and application of systems, structures and devices with novel functions obtained via precursor nanoparticles is emphasized. Approaches may include gas-, liquid-, solid-, and vacuum-based processes, size reduction, chemical- and bio-self assembly. Contributions include utilization of nanoparticle systems for enhancing a phenomenon or process and particle assembling into hierarchical structures, as well as formulation and the administration of drugs. Synergistic approaches originating from different disciplines and technologies, and interaction between the research providers and users in this field, are encouraged.