Yuanchao Xue, Filipe M. Cerqueira, Heather L. Stevenson, Natalie Williams-Bouyer, Rong Fang
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Culture-negative liver abscess identified with plasma microbial cell-free DNA sequencing: A case report
Pyogenic liver abscess (PLA) is a potentially life-threatening disease. Early diagnosis and appropriate treatment are crucial to ensure high-quality healthcare for patients with PLA. However, this is complicated by their non-specific clinical symptoms. In addition, the etiologic organisms responsible for PLA are frequently culture-negative, thus complicating clinical decision-making. Here, we report a case of PLA caused by Streptococcus intermedius, as identified via DNA metagenomic sequencing of plasma.
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