利用Perturb-FISH研究空间基因回路和基因表型机制。

IF 52 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2025-05-20 DOI:10.1038/s41576-025-00857-8

Loïc Binan

引用次数: 0

摘要

在这篇贸易工具文章中，Loic Binan解释了Perturb-FISH，它以高通量测量遗传扰动和基因原位表达，以绘制细胞和组织尺度上的基因调控网络。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Investigating spatial gene circuits and gene–phenotype mechanisms with Perturb-FISH

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Investigating spatial gene circuits and gene–phenotype mechanisms with Perturb-FISH

In this Tools of the Trade article, Loic Binan explains Perturb-FISH, which measures genetic perturbations and gene expression in situ at high throughput to map gene regulatory networks at cellular and tissue scale.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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