{"title":"反复着床失败妇女的新鲜胚胎移植与冷冻胚胎移植。","authors":"Saeideh Dashti, Sahereh Arabian, Robab Davar","doi":"10.4103/abr.abr_541_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>To compare the outcomes of fresh embryo transfer (ET) versus frozen ET (FET) in women with recurrent implantation failure (RIF).</p><p><strong>Materials and methods: </strong>This retrospective cohort study was performed at Yazd Reproductive Sciences Institute. A total of 498 cycles, including 418 FET cycles and 80 fresh cycles, from women with RIF were reviewed between February 2020 and February 2023. The chemical and clinical pregnancy rates and live birth rate were compared.</p><p><strong>Results: </strong>FET cycles demonstrated significantly higher rates of both chemical (29.7% vs 13.8%, <i>P</i> = 0.002) and clinical pregnancy (20.6% vs 10.0%, <i>P</i> = 0.027) compared to fresh ET cycles. The live birth rate in the frozen transfer group was higher compared to the fresh transfer group, but the difference was not statistically significant (8.7% vs 4.9%, <i>P</i> value = 0.127).</p><p><strong>Conclusions: </strong>Our findings showed that FET cycles may be associated with improved pregnancy rates in women with RIF.</p>","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"14 ","pages":"36"},"PeriodicalIF":0.7000,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087930/pdf/","citationCount":"0","resultStr":"{\"title\":\"Fresh Versus Frozen Embryo Transfer in Women with Repeated Implantation Failure.\",\"authors\":\"Saeideh Dashti, Sahereh Arabian, Robab Davar\",\"doi\":\"10.4103/abr.abr_541_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>To compare the outcomes of fresh embryo transfer (ET) versus frozen ET (FET) in women with recurrent implantation failure (RIF).</p><p><strong>Materials and methods: </strong>This retrospective cohort study was performed at Yazd Reproductive Sciences Institute. A total of 498 cycles, including 418 FET cycles and 80 fresh cycles, from women with RIF were reviewed between February 2020 and February 2023. The chemical and clinical pregnancy rates and live birth rate were compared.</p><p><strong>Results: </strong>FET cycles demonstrated significantly higher rates of both chemical (29.7% vs 13.8%, <i>P</i> = 0.002) and clinical pregnancy (20.6% vs 10.0%, <i>P</i> = 0.027) compared to fresh ET cycles. The live birth rate in the frozen transfer group was higher compared to the fresh transfer group, but the difference was not statistically significant (8.7% vs 4.9%, <i>P</i> value = 0.127).</p><p><strong>Conclusions: </strong>Our findings showed that FET cycles may be associated with improved pregnancy rates in women with RIF.</p>\",\"PeriodicalId\":94292,\"journal\":{\"name\":\"Advanced biomedical research\",\"volume\":\"14 \",\"pages\":\"36\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-04-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087930/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced biomedical research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/abr.abr_541_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced biomedical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/abr.abr_541_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
摘要
背景：比较新鲜胚胎移植（ET）和冷冻胚胎移植（FET）治疗复发性胚胎植入失败（RIF）的结果。材料和方法：本回顾性队列研究在亚兹德生殖科学研究所进行。在2020年2月至2023年2月期间，对来自RIF妇女的498个周期进行了审查，其中包括418个FET周期和80个新鲜周期。比较化学妊娠率、临床妊娠率和活产率。结果：与新鲜ET周期相比，FET周期的化学发生率（29.7% vs 13.8%, P = 0.002）和临床妊娠率（20.6% vs 10.0%, P = 0.027）均显著高于新鲜ET周期。冷冻移植组活产率高于新鲜移植组，但差异无统计学意义（8.7% vs 4.9%， P值= 0.127）。结论：我们的研究结果表明，FET周期可能与RIF妇女妊娠率的提高有关。
Fresh Versus Frozen Embryo Transfer in Women with Repeated Implantation Failure.
Background: To compare the outcomes of fresh embryo transfer (ET) versus frozen ET (FET) in women with recurrent implantation failure (RIF).
Materials and methods: This retrospective cohort study was performed at Yazd Reproductive Sciences Institute. A total of 498 cycles, including 418 FET cycles and 80 fresh cycles, from women with RIF were reviewed between February 2020 and February 2023. The chemical and clinical pregnancy rates and live birth rate were compared.
Results: FET cycles demonstrated significantly higher rates of both chemical (29.7% vs 13.8%, P = 0.002) and clinical pregnancy (20.6% vs 10.0%, P = 0.027) compared to fresh ET cycles. The live birth rate in the frozen transfer group was higher compared to the fresh transfer group, but the difference was not statistically significant (8.7% vs 4.9%, P value = 0.127).
Conclusions: Our findings showed that FET cycles may be associated with improved pregnancy rates in women with RIF.
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