{"title":"孔源性视网膜脱离术后1个月硅油填塞的疗效：一项多中心研究。","authors":"Jingyi Li, Wei Wu, Chunling Huang, Yulin Ma, Pengtao Gu, Qiuxia Lin, Jiaqi Liu, Porpor Kea, Yonggang Yuan, Ling Lin, Peiyang Shen, Jiali Li, Songfu Feng","doi":"10.1159/000546255","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The aim of study was to investigate postoperative outcomes in patients who underwent rhegmatogenous retinal detachment (RRD) surgery.</p><p><strong>Methods: </strong>This was a multicenter retrospective study involving 263 patients who underwent silicone oil (SiO) tamponade for RRD. Patients were divided into three groups based on the SiO tamponade: 1 month (group 1, n = 55), 3 months (group 2, n = 176), and 6 months (group 3, n = 32). The main outcomes were best-corrected visual acuity (BCVA), intraocular pressure (IOP), and retinal structure 1 month after silicone oil removal (SOR).</p><p><strong>Results: </strong>In the analysis of retinal structure in post-SOR, the median central macular thickness (CMT) in groups 1, 2, and 3 was 182.5 μm (IQR: 156.0-214.0), 170.0 μm (IQR: 140.3-211.5), and 152.0 μm (IQR: 92.3-195.3), and the median ganglion cell layer-inner plexiform layer (GCL-IPL) in groups 1, 2, and 3 was 80.5 μm (IQR: 70.0-92.3), 73.0 μm (IQR: 65.0-81.3), and 65.0 μm (IQR: 56.3-79.0), respectively. Both CMT and GCL-IPL differed significantly with the group 1 exhibiting the thickest retinal structure (p = 0.03 and p = 0.006). IOP differed significantly across groups, with group 3 showing the highest IOP in post-SOR (p = 0.015). However, there were no significant differences in BCVA, inner retinal layer thickness, outer retinal layer thickness, or submacular fluid among the groups.</p><p><strong>Conclusions: </strong>Prolonged SiO tamponade is correlated with increased IOP and the thinning of the CMT and GCL-IPL over time, with favorable postoperative outcomes for 1-month SiO tamponade. Given the potential risks of extended tamponade, it is advisable to remove SiO as soon as anatomically feasible.</p>","PeriodicalId":19662,"journal":{"name":"Ophthalmic Research","volume":" ","pages":"333-341"},"PeriodicalIF":1.9000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Postoperative Outcomes of 1-Month Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment: A Multicenter Study.\",\"authors\":\"Jingyi Li, Wei Wu, Chunling Huang, Yulin Ma, Pengtao Gu, Qiuxia Lin, Jiaqi Liu, Porpor Kea, Yonggang Yuan, Ling Lin, Peiyang Shen, Jiali Li, Songfu Feng\",\"doi\":\"10.1159/000546255\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The aim of study was to investigate postoperative outcomes in patients who underwent rhegmatogenous retinal detachment (RRD) surgery.</p><p><strong>Methods: </strong>This was a multicenter retrospective study involving 263 patients who underwent silicone oil (SiO) tamponade for RRD. Patients were divided into three groups based on the SiO tamponade: 1 month (group 1, n = 55), 3 months (group 2, n = 176), and 6 months (group 3, n = 32). The main outcomes were best-corrected visual acuity (BCVA), intraocular pressure (IOP), and retinal structure 1 month after silicone oil removal (SOR).</p><p><strong>Results: </strong>In the analysis of retinal structure in post-SOR, the median central macular thickness (CMT) in groups 1, 2, and 3 was 182.5 μm (IQR: 156.0-214.0), 170.0 μm (IQR: 140.3-211.5), and 152.0 μm (IQR: 92.3-195.3), and the median ganglion cell layer-inner plexiform layer (GCL-IPL) in groups 1, 2, and 3 was 80.5 μm (IQR: 70.0-92.3), 73.0 μm (IQR: 65.0-81.3), and 65.0 μm (IQR: 56.3-79.0), respectively. Both CMT and GCL-IPL differed significantly with the group 1 exhibiting the thickest retinal structure (p = 0.03 and p = 0.006). IOP differed significantly across groups, with group 3 showing the highest IOP in post-SOR (p = 0.015). However, there were no significant differences in BCVA, inner retinal layer thickness, outer retinal layer thickness, or submacular fluid among the groups.</p><p><strong>Conclusions: </strong>Prolonged SiO tamponade is correlated with increased IOP and the thinning of the CMT and GCL-IPL over time, with favorable postoperative outcomes for 1-month SiO tamponade. Given the potential risks of extended tamponade, it is advisable to remove SiO as soon as anatomically feasible.</p>\",\"PeriodicalId\":19662,\"journal\":{\"name\":\"Ophthalmic Research\",\"volume\":\" \",\"pages\":\"333-341\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ophthalmic Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/000546255\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ophthalmic Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000546255","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Postoperative Outcomes of 1-Month Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment: A Multicenter Study.
Introduction: The aim of study was to investigate postoperative outcomes in patients who underwent rhegmatogenous retinal detachment (RRD) surgery.
Methods: This was a multicenter retrospective study involving 263 patients who underwent silicone oil (SiO) tamponade for RRD. Patients were divided into three groups based on the SiO tamponade: 1 month (group 1, n = 55), 3 months (group 2, n = 176), and 6 months (group 3, n = 32). The main outcomes were best-corrected visual acuity (BCVA), intraocular pressure (IOP), and retinal structure 1 month after silicone oil removal (SOR).
Results: In the analysis of retinal structure in post-SOR, the median central macular thickness (CMT) in groups 1, 2, and 3 was 182.5 μm (IQR: 156.0-214.0), 170.0 μm (IQR: 140.3-211.5), and 152.0 μm (IQR: 92.3-195.3), and the median ganglion cell layer-inner plexiform layer (GCL-IPL) in groups 1, 2, and 3 was 80.5 μm (IQR: 70.0-92.3), 73.0 μm (IQR: 65.0-81.3), and 65.0 μm (IQR: 56.3-79.0), respectively. Both CMT and GCL-IPL differed significantly with the group 1 exhibiting the thickest retinal structure (p = 0.03 and p = 0.006). IOP differed significantly across groups, with group 3 showing the highest IOP in post-SOR (p = 0.015). However, there were no significant differences in BCVA, inner retinal layer thickness, outer retinal layer thickness, or submacular fluid among the groups.
Conclusions: Prolonged SiO tamponade is correlated with increased IOP and the thinning of the CMT and GCL-IPL over time, with favorable postoperative outcomes for 1-month SiO tamponade. Given the potential risks of extended tamponade, it is advisable to remove SiO as soon as anatomically feasible.
期刊介绍：
''Ophthalmic Research'' features original papers and reviews reporting on translational and clinical studies. Authors from throughout the world cover research topics on every field in connection with physical, physiologic, pharmacological, biochemical and molecular biological aspects of ophthalmology. This journal also aims to provide a record of international clinical research for both researchers and clinicians in ophthalmology. Finally, the transfer of information from fundamental research to clinical research and clinical practice is particularly welcome.
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