持续性伤口：肛周瘘管的浆母细胞淋巴瘤。

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-05-17 eCollection Date: 2025-05-01 DOI:10.14309/crj.0000000000001705

Salim C Lutfallah, John F G Bobo, Rachna Jetly-Shridhar, Nisha Loganantharaj

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引用次数: 0

摘要

浆母细胞淋巴瘤是一种与免疫抑制相关的弥漫性大b细胞淋巴瘤的侵袭性亚型，特别是在hiv阳性患者中。虽然在hiv阴性个体中罕见，但克罗恩病患者由于慢性免疫抑制而经历免疫失调，这可能使他们易患浆母细胞淋巴瘤。我们报告一例54岁男性回肠和肛周瘘管性克罗恩病发展为浆母细胞淋巴瘤。本病例强调了在接受克罗恩病慢性免疫抑制治疗的患者中早期识别浆母细胞淋巴瘤的重要性，因为早期诊断和及时干预对于改善预后至关重要。

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The Persistent Wound: Plasmablastic Lymphoma in a Perianal Fistula.

Plasmablastic lymphoma is an aggressive subtype of diffuse large B-cell lymphoma associated with immunosuppression, particularly in HIV-positive patients. Although rare in HIV-negative individuals, patients with Crohn's disease experience immune dysregulation due to chronic immunosuppression that can predispose them to plasmablastic lymphoma. We present a case of a 54-year-old man with ileocolonic and perianal fistulizing Crohn's disease who developed plasmablastic lymphoma. This case emphasizes the importance of early recognition of plasmablastic lymphoma in patients undergoing chronic immunosuppressive treatment of Crohn's disease, as early diagnosis and timely intervention are crucial for improving outcomes.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.