多系统IgG4相关疾病的超声检查：5年随访病例报告

IF 1.7 4区综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES

Journal of Radiation Research and Applied Sciences Pub Date : 2025-05-20 DOI:10.1016/j.jrras.2025.101629

Min Wang , Deli Meng , Lingling Xing , Fei Xu , Fengfeng Ding , Yanglieguang Lou

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引用次数: 0

摘要

igg4相关疾病（IgG4-RD）是一种慢性纤维化全身性疾病，因其肿块样病变常被误诊为肿瘤。本病例报告了2019年诊断为IgG4- rd的患者，其特征是血清IgG4升高，肝肾功能受损，补体减少，肺间质改变，胆管狭窄，肾脏肿大，下颌下/甲状腺肿胀。患者最初通过糖皮质激素治疗获得缓解，但5年后，即2024年，患者病情恶化，PET/CT显示胰腺肿块和淋巴结肿大。超声引导活检证实患者患有igg4相关的自身免疫性胰腺炎，而不是癌症。本病例说明了超声成像在长期随访中对IgG4-RD的疾病检测和治疗监测中的关键作用。

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Ultrasonography of IgG4 related diseases involving multiple systems: a five-year follow-up case report

IgG4-related disease (IgG4-RD), a chronic fibrosing systemic disease, is usually misdiagnosed as a tumor due to its mass-like lesions. This case reports a patient diagnosed with IgG4-RD in 2019, characterized by elevated serum IgG4, impaired liver/kidney function, decreased complement, interstitial lung changes, bile duct narrowing, enlarged kidneys, and swollen submandibular/thyroid glands. The patient initially achieved remission with glucocorticoid therapy, but after 5 years, in 2024, the patient's condition worsened, and PET/CT showed a pancreatic mass and enlarged lymph nodes. Ultrasound-guided biopsy confirmed the patient had IgG4-related autoimmune pancreatitis, not cancer. This case illustrates the critical role of ultrasound imaging in disease detection and treatment monitoring of IgG4-RD during long-term follow-up.

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来源期刊

Journal of Radiation Research and Applied Sciences MULTIDISCIPLINARY SCIENCES-

自引率

5.90%

发文量

130

审稿时长

16 weeks

期刊介绍： Journal of Radiation Research and Applied Sciences provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and applications of nuclear, radiation and isotopes in biology, medicine, drugs, biochemistry, microbiology, agriculture, entomology, food technology, chemistry, physics, solid states, engineering, environmental and applied sciences.