2016-2023年墨西哥诊断为糖尿病的成人心血管风险管理:对全国代表性调查的回顾性分析

Daniel Ramírez-García, Jerónimo Perezalonso-Espinosa, Padme Nailea Méndez-Labra, Carlos A Fermín-Martínez, Juan Pablo Díaz-Sánchez, César Daniel Paz-Cabrera, Arsenio Vargas-Vázquez, Miriam Teresa López-Teros, David Flood, Jennifer Manne-Goehler, Neftali Eduardo Antonio-Villa, Goodarz Danaei, Jacqueline A Seiglie, Omar Yaxmehen Bello-Chavolla
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引用次数: 0

摘要

背景:有效的心血管疾病(CVD)风险管理是优化糖尿病护理的基石。在这里,我们估计了墨西哥诊断为糖尿病的个体中CVD危险因素控制的患病率和决定因素。方法:我们分析了2016-2023年墨西哥国家健康与营养调查中诊断为糖尿病≥20岁的个体的数据。我们估计了血糖、血压(BP)、不吸烟和心血管疾病危险因素综合控制的患病率。使用score2 -糖尿病风险分类评估LDL-C控制。我们估计了降血压、降胆固醇和降血糖药物使用的流行程度,并利用逻辑回归探讨了控制效果的决定因素。结果:我们分析了2016-2023年间诊断为糖尿病的4320万成年人的数据。2023年,血糖控制为29% (95%CI 21%-38%),血压控制为22.9% (95%CI 14%-31%),不吸烟为89% (95%CI 81%-96%)。被归类为高或极高心血管疾病风险的人群比例从2016年的59.8% (95%CI 52.1%-67.0%)增加到2023年的68.4% (95%CI 55.6%-78.9%),代表约510万成年人。LDL-C控制患病率从2016年的2.8% (95%CI 1.2%-4.4%)上升到2023年的6.6% (95%CI 1.9%-11.2%)。综合危险因素控制的效果较低,主要是由于LDL-C控制不理想,尽管药物使用率很高;这在女性、年轻人、受过大学教育或生活在社会经济地位较高的州的人身上更有可能实现。结论:尽管在此期间CVD风险增加,但墨西哥成人糖尿病患者的综合血糖和CVD危险因素管理仍然不理想。我们的研究结果强调需要制定策略来解决心血管疾病风险管理方面的差距,以减少这一人群的过早死亡。概要:这项研究调查了墨西哥的成人糖尿病患者如何控制心血管疾病的关键风险因素,如血糖水平、血压、吸烟和胆固醇水平。作者使用了2016-2023年具有全国代表性的调查,分析了超过4320万确诊糖尿病患者的数据。2023年,尽管药物使用率很高,但不到三分之一的糖尿病患者血糖得到适当控制,不到十分之一的糖尿病患者达到了推荐的胆固醇目标。2016年至2023年间,高危人群的心血管风险增加了近9%。在女性、年轻人、受过高等教育的人和生活在社会经济优势地区的人中,对这些风险因素的更好控制更为常见。图形化的简介:
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiovascular risk management in adults with diagnosed diabetes in Mexico from 2016-2023: A retrospective analysis of nationally representative surveys.

Background: Effective cardiovascular disease (CVD) risk management is a cornerstone of optimal diabetes care. Here, we estimated the prevalence and determinants of CVD risk factor control amongst individuals with diagnosed diabetes in Mexico.

Methods: We analyzed data from individuals with diagnosed diabetes ≥20 years from the 2016-2023 Mexican National Health and Nutrition Surveys. We estimated the prevalence of glycemic, blood pressure (BP), non-current smoking, and combined CVD risk factor control. LDL-C control was assessed using SCORE2-Diabetes risk categories. We estimated the prevalence of BP-lowering, cholesterol-lowering, and glucose-lowering medication use, and explored determinants of control achievement using logistic regression.

Results: We analyzed data representing 43.2 million adults with diagnosed diabetes during 2016-2023. In 2023, glycemic control was 29% (95%CI 21%-38%), BP control 22.9% (95%CI 14%-31%), and non-current smoking 89% (95%CI 81%-96%). The proportion of people classified as high or very-high CVD risk increased from 59.8% (95%CI 52.1%-67.0%) in 2016 to 68.4% (95%CI 55.6%-78.9%) in 2023, representing ~5.1 million adults. LDL-C control prevalence increased from 2.8% (95%CI 1.2%-4.4%) in 2016 to 6.6% (95%CI 1.9%-11.2%) in 2023. Combined risk factor control achievement was low primarily due to suboptimal LDL-C control, despite high medication use; this was more likely achieved in females, younger individuals, and those with college education or living in states with higher socioeconomic position.

Conclusions: Despite increasing CVD risk during this period, comprehensive glycemic and CVD risk factor management for adults with diabetes in Mexico remains suboptimal. Our findings highlight the need for strategies to address gaps in CVD risk management to reduce premature mortality in this population.

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