Nicolò Marchesini , Riya Mandar Dange , Andreas K. Demetriades , Oscar Alves , Amos Olufemi Adeleye , Ernest J. Barthélemy , José Castillo , Juan Diego Ciro , Raul Echeverri , Kiwon Lee , Wellingson Paiva , Julio Pozuelos , Martin Aliaga Rocabado , Alvaro Soto , Gene Y. Sung , Andrès M. Rubiano , BOOTStraP-SCI Study Group
{"title":"脊髓损伤和脊髓损伤的治疗方案:基于共识的重症监护和外科治疗分层方案。","authors":"Nicolò Marchesini , Riya Mandar Dange , Andreas K. Demetriades , Oscar Alves , Amos Olufemi Adeleye , Ernest J. Barthélemy , José Castillo , Juan Diego Ciro , Raul Echeverri , Kiwon Lee , Wellingson Paiva , Julio Pozuelos , Martin Aliaga Rocabado , Alvaro Soto , Gene Y. Sung , Andrès M. Rubiano , BOOTStraP-SCI Study Group","doi":"10.1016/j.wneu.2025.124099","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Spinal trauma (STx), with or without spinal cord injury (SCI), represents a significant global health burden, particularly in low- and middle-income countries (LMICs). International guidelines often assume the availability of resources for intensive care and surgical management, limiting their applicability in resource-constrained settings. A resource-adapted approach may improve management in these contexts. This study aimed to develop resource-tiered protocols for the intensive care and surgical management of STx and SCI, addressing LMIC-specific challenges with clinical evidence and expert-based practices.</div></div><div><h3>Methods</h3><div>A multidisciplinary Delphi consensus process combined international evidence-based guidelines with expert input. Iterative discussions and voting by healthcare providers from LMICs and high-income countries ensured context-sensitive and flexible protocols, tailored to varying levels of training, resource availability, and healthcare infrastructure.</div></div><div><h3>Results</h3><div>The resulting protocols address key aspects of intensive care and surgical management, including resuscitation, cardiopulmonary optimization, imaging, and surgical criteria and timing. Two protocols were developed for intensive care (postoperative recovery and general ICU setting) and 3 for surgical management, reflecting resource levels: basic facilities without imaging, intermediate facilities with X-ray, and advanced facilities with computed tomography and magnetic resonance imaging.</div></div><div><h3>Conclusions</h3><div>The proposed protocols may bridge gaps in STx and SCI care in LMICs by providing adaptable frameworks for resource-limited contexts. The consensus-driven approach can foster protocolized care delivery in LMICs, emphasizing feasibility and local adaptability. Future efforts should focus on validating these protocols in clinical practice.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"200 ","pages":"Article 124099"},"PeriodicalIF":1.9000,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"BOOTStrap-SCI: Beyond One Option of Treatment for Spinal Trauma and Spinal Cord Injury: Consensus-Based Stratified Protocols for Intensive Care and Surgical Management\",\"authors\":\"Nicolò Marchesini , Riya Mandar Dange , Andreas K. Demetriades , Oscar Alves , Amos Olufemi Adeleye , Ernest J. Barthélemy , José Castillo , Juan Diego Ciro , Raul Echeverri , Kiwon Lee , Wellingson Paiva , Julio Pozuelos , Martin Aliaga Rocabado , Alvaro Soto , Gene Y. Sung , Andrès M. Rubiano , BOOTStraP-SCI Study Group\",\"doi\":\"10.1016/j.wneu.2025.124099\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>Spinal trauma (STx), with or without spinal cord injury (SCI), represents a significant global health burden, particularly in low- and middle-income countries (LMICs). International guidelines often assume the availability of resources for intensive care and surgical management, limiting their applicability in resource-constrained settings. A resource-adapted approach may improve management in these contexts. This study aimed to develop resource-tiered protocols for the intensive care and surgical management of STx and SCI, addressing LMIC-specific challenges with clinical evidence and expert-based practices.</div></div><div><h3>Methods</h3><div>A multidisciplinary Delphi consensus process combined international evidence-based guidelines with expert input. Iterative discussions and voting by healthcare providers from LMICs and high-income countries ensured context-sensitive and flexible protocols, tailored to varying levels of training, resource availability, and healthcare infrastructure.</div></div><div><h3>Results</h3><div>The resulting protocols address key aspects of intensive care and surgical management, including resuscitation, cardiopulmonary optimization, imaging, and surgical criteria and timing. Two protocols were developed for intensive care (postoperative recovery and general ICU setting) and 3 for surgical management, reflecting resource levels: basic facilities without imaging, intermediate facilities with X-ray, and advanced facilities with computed tomography and magnetic resonance imaging.</div></div><div><h3>Conclusions</h3><div>The proposed protocols may bridge gaps in STx and SCI care in LMICs by providing adaptable frameworks for resource-limited contexts. The consensus-driven approach can foster protocolized care delivery in LMICs, emphasizing feasibility and local adaptability. Future efforts should focus on validating these protocols in clinical practice.</div></div>\",\"PeriodicalId\":23906,\"journal\":{\"name\":\"World neurosurgery\",\"volume\":\"200 \",\"pages\":\"Article 124099\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-05-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World neurosurgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1878875025004553\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World neurosurgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878875025004553","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
BOOTStrap-SCI: Beyond One Option of Treatment for Spinal Trauma and Spinal Cord Injury: Consensus-Based Stratified Protocols for Intensive Care and Surgical Management
Objective
Spinal trauma (STx), with or without spinal cord injury (SCI), represents a significant global health burden, particularly in low- and middle-income countries (LMICs). International guidelines often assume the availability of resources for intensive care and surgical management, limiting their applicability in resource-constrained settings. A resource-adapted approach may improve management in these contexts. This study aimed to develop resource-tiered protocols for the intensive care and surgical management of STx and SCI, addressing LMIC-specific challenges with clinical evidence and expert-based practices.
Methods
A multidisciplinary Delphi consensus process combined international evidence-based guidelines with expert input. Iterative discussions and voting by healthcare providers from LMICs and high-income countries ensured context-sensitive and flexible protocols, tailored to varying levels of training, resource availability, and healthcare infrastructure.
Results
The resulting protocols address key aspects of intensive care and surgical management, including resuscitation, cardiopulmonary optimization, imaging, and surgical criteria and timing. Two protocols were developed for intensive care (postoperative recovery and general ICU setting) and 3 for surgical management, reflecting resource levels: basic facilities without imaging, intermediate facilities with X-ray, and advanced facilities with computed tomography and magnetic resonance imaging.
Conclusions
The proposed protocols may bridge gaps in STx and SCI care in LMICs by providing adaptable frameworks for resource-limited contexts. The consensus-driven approach can foster protocolized care delivery in LMICs, emphasizing feasibility and local adaptability. Future efforts should focus on validating these protocols in clinical practice.
期刊介绍:
World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The journal''s mission is to:
-To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care.
-To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide.
-To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients.
Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS