延伸波沿肌纤维的传播源于端板区域的早期局部收缩。

IF 2.6 4区 医学 Q2 PHYSIOLOGY
Tomonori Hayashi, Naoya Nakahara, Shigeru Morimoto, Maki Yamaguchi, Kazuhiro Hirano, Shigeru Takemori
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引用次数: 0

摘要

我们研究了由端板区域早期局部收缩的内部缩短引发的延伸波沿抽搐肌纤维的传播。对牛蛙缝匠肌进行了最低限度的刺激,并用高速摄像机捕捉到了附着在肌肉表面的碳颗粒的位移。我们发现沿纤维延伸的波的速度为5.35±0.33 m·s⁻¹,比动作电位的传导速度3.04±0.31 m·s⁻¹要快。肌肉表面的局部压缩阻止了延伸波的传播,表明其力学性质。肌肉伸展使延伸波速度增加。这些发现提供了直接证据,证明机械传递的延伸波起源于终板区域的早期局部收缩,并在收缩波之前沿着肌纤维传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Extending wave propagation along muscle fibers originates from early local contraction at the end-plate region.

We investigated the propagation of extending waves along twitching muscle fibers triggered by the internal shortening of early local contraction in the end-plate region. Bullfrog sartorius muscles were minimally stimulated, and the displacement of carbon particles attached to the muscle surface was captured using a high-speed camera. We found an extending wave along the fiber at a velocity of 5.35 ± 0.33 m·s⁻¹, faster than the conduction of action potentials at 3.04 ± 0.31 m·s⁻¹. Local compression of the muscle surface blocked the propagation of the extending wave, indicating its mechanical nature. Muscle stretching increased the extending wave velocity. These findings provide direct evidence that mechanically transmitted extending waves originate from early local contractions in the end-plate region and propagate along muscle fibers ahead of the contraction wave.

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来源期刊
CiteScore
4.40
自引率
4.30%
发文量
27
审稿时长
6-12 weeks
期刊介绍: The Journal of Physiological Sciences publishes peer-reviewed original papers, reviews, short communications, technical notes, and letters to the editor, based on the principles and theories of modern physiology and addressed to the international scientific community. All fields of physiology are covered, encompassing molecular, cellular and systems physiology. The emphasis is on human and vertebrate physiology, but comparative papers are also considered. The process of obtaining results must be ethically sound. Fields covered: Adaptation and environment Autonomic nervous function Biophysics Cell sensors and signaling Central nervous system and brain sciences Endocrinology and metabolism Excitable membranes and neural cell physiology Exercise physiology Gastrointestinal and kidney physiology Heart and circulatory physiology Molecular and cellular physiology Muscle physiology Physiome/systems biology Respiration physiology Senses.
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