Li Ma, Jie Hao, Saijun Wang, Kaiyin Yang, Wansheng Liang, Fengxiang Gu
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The predictive value of significant factors was assessed using receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>The incidence of POD was significantly higher in the GA group than that in the SA group (27.4% vs. 9.9%, P=0.002). The visual analogue scale scores at 24 hours postoperatively and analgesic drug usage were significantly higher in the GA group (both P<0.001). Cognitive function scores postoperatively were significantly lower in the GA group (P<0.005). Multivariate analysis identified longer operation time (P<0.001, OR: 1.084, 95% CI: 1.047-1.123) and higher intraoperative blood loss (P=0.042, OR: 1.018, 95% CI: 1.001-1.035) as independent risk factors for POD. Conversely, higher preoperative hemoglobin (P=0.002, OR: 0.949, 95% CI: 0.919-0.981) and SA (P=0.021, OR: 0.174, 95% CI: 0.039-0.767) were protective factors.</p><p><strong>Conclusion: </strong>Compared to GA, SA significantly reduces POD incidence and improves postoperative analgesia in elderly hip fracture patients. Optimizing anesthetic strategies and preoperative assessments may enhance postoperative recovery in this population.</p>","PeriodicalId":7731,"journal":{"name":"American journal of translational research","volume":"17 4","pages":"2937-2946"},"PeriodicalIF":1.6000,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082509/pdf/","citationCount":"0","resultStr":"{\"title\":\"Impact of general anesthesia and spinal anesthesia on postal delirium and risk factors in elderly patients undergoing hip fracture surgery.\",\"authors\":\"Li Ma, Jie Hao, Saijun Wang, Kaiyin Yang, Wansheng Liang, Fengxiang Gu\",\"doi\":\"10.62347/NKTA3087\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To compare the effects of general anesthesia (GA) and spinal anesthesia (SA) on postoperative delirium (POD) in elderly patients undergoing hip fracture surgery and to identify associated risk factors.</p><p><strong>Methods: </strong>A retrospective study was conducted on 186 elderly patients who underwent hip fracture surgery at the Affiliated Hospital of Gansu University of Chinese Medicine from January 2021 to January 2023. Patients were categorized into GA and SA groups. The incidence of POD, postoperative pain control, and cognitive function changes were compared. Univariate and multivariate Logistic regression analyses were performed to identify independent risk factors for POD. The predictive value of significant factors was assessed using receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>The incidence of POD was significantly higher in the GA group than that in the SA group (27.4% vs. 9.9%, P=0.002). The visual analogue scale scores at 24 hours postoperatively and analgesic drug usage were significantly higher in the GA group (both P<0.001). Cognitive function scores postoperatively were significantly lower in the GA group (P<0.005). Multivariate analysis identified longer operation time (P<0.001, OR: 1.084, 95% CI: 1.047-1.123) and higher intraoperative blood loss (P=0.042, OR: 1.018, 95% CI: 1.001-1.035) as independent risk factors for POD. Conversely, higher preoperative hemoglobin (P=0.002, OR: 0.949, 95% CI: 0.919-0.981) and SA (P=0.021, OR: 0.174, 95% CI: 0.039-0.767) were protective factors.</p><p><strong>Conclusion: </strong>Compared to GA, SA significantly reduces POD incidence and improves postoperative analgesia in elderly hip fracture patients. Optimizing anesthetic strategies and preoperative assessments may enhance postoperative recovery in this population.</p>\",\"PeriodicalId\":7731,\"journal\":{\"name\":\"American journal of translational research\",\"volume\":\"17 4\",\"pages\":\"2937-2946\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082509/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of translational research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.62347/NKTA3087\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of translational research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.62347/NKTA3087","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
摘要
目的:比较全身麻醉(GA)与脊髓麻醉(SA)对老年髋部骨折术后谵妄(POD)的影响,并探讨相关危险因素。方法:对2021年1月至2023年1月在甘肃中医药大学附属医院行髋部骨折手术的老年患者186例进行回顾性研究。患者分为GA组和SA组。比较POD发生率、术后疼痛控制和认知功能变化。进行单因素和多因素Logistic回归分析以确定POD的独立危险因素。采用受试者工作特征(ROC)曲线分析评估显著因素的预测价值。结果:GA组POD发生率明显高于SA组(27.4% vs. 9.9%, P=0.002)。结论:与GA相比,SA可显著降低老年髋部骨折患者POD的发生率,改善术后镇痛效果。优化麻醉策略和术前评估可以提高这一人群的术后恢复。
Impact of general anesthesia and spinal anesthesia on postal delirium and risk factors in elderly patients undergoing hip fracture surgery.
Objective: To compare the effects of general anesthesia (GA) and spinal anesthesia (SA) on postoperative delirium (POD) in elderly patients undergoing hip fracture surgery and to identify associated risk factors.
Methods: A retrospective study was conducted on 186 elderly patients who underwent hip fracture surgery at the Affiliated Hospital of Gansu University of Chinese Medicine from January 2021 to January 2023. Patients were categorized into GA and SA groups. The incidence of POD, postoperative pain control, and cognitive function changes were compared. Univariate and multivariate Logistic regression analyses were performed to identify independent risk factors for POD. The predictive value of significant factors was assessed using receiver operating characteristic (ROC) curve analysis.
Results: The incidence of POD was significantly higher in the GA group than that in the SA group (27.4% vs. 9.9%, P=0.002). The visual analogue scale scores at 24 hours postoperatively and analgesic drug usage were significantly higher in the GA group (both P<0.001). Cognitive function scores postoperatively were significantly lower in the GA group (P<0.005). Multivariate analysis identified longer operation time (P<0.001, OR: 1.084, 95% CI: 1.047-1.123) and higher intraoperative blood loss (P=0.042, OR: 1.018, 95% CI: 1.001-1.035) as independent risk factors for POD. Conversely, higher preoperative hemoglobin (P=0.002, OR: 0.949, 95% CI: 0.919-0.981) and SA (P=0.021, OR: 0.174, 95% CI: 0.039-0.767) were protective factors.
Conclusion: Compared to GA, SA significantly reduces POD incidence and improves postoperative analgesia in elderly hip fracture patients. Optimizing anesthetic strategies and preoperative assessments may enhance postoperative recovery in this population.