活细胞g -四重体成像用聚甲基链修饰五亚甲基菁染料的构建。

IF 4.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-05-19 DOI:10.1039/d5cc00436e

Li Guan, Jun Li, Yanyan Zhou, Anyang Li, Lili Yin, Wenhui Guan, Yile Fu

引用次数: 0

摘要

本文概述了一种依赖于g -四重体DNA识别驱动的五亚甲基花菁Cy5-ph-H聚集体分解的超分子策略，该策略可以打开其荧光，并用于可视化活细胞中的g -四重体DNA和高度靶向线粒体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Construction of polymethine chain-modified pentamethylene cyanine dyes for G-quadruplex imaging in live cells.

Here, a supramolecular strategy that relies on the G-quadruplex DNA recognition-driven disaggregation of pentamethylene cyanine Cy5-ph-H aggregates is outlined, which can turn on its fluorescence and be used to visualize G-quadruplex DNA in living cells and highly target mitochondria.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.