复杂磁场:利用电磁交响乐在再生医学和抗真菌特性方面的可能应用

IF 2.6 3区 医学 Q2 DERMATOLOGY
Muhammad Dawood Amjad, Lorenzo Marramiero, Tea Romasco, Alessandro Cipollina, Hamid Heydari Sheikh Hossein, Marco Mantarro, Adriano Piattelli, Stefania Fulle, Natalia Di Pietro, Rosa Mancinelli
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引用次数: 0

摘要

复合磁场(CMFs)代表了再生医学的新兴前沿,为创新治疗策略提供了巨大的潜力。本文综述了CMFs的理论基础和实际应用,重点介绍了CMFs在组织再生和抗真菌活性方面的作用。对电子数据库(PubMed、Scopus和Embase)的全面回顾确定了有关CMF主题的7项关键体外模型研究。尽管研究数量有限,但它们共同强调了CMFs在促进伤口愈合、减少氧化应激和糖尿病神经病变的神经炎症、积极影响线粒体功能、调节免疫反应、促进细胞通讯、抑制白色念珠菌对医疗表面的生长和粘附以及促进炎症条件下牙髓干细胞增殖方面的治疗潜力。这些发现表明,CMFs可能提供一种生态可持续的方法,有效地靶向病原体,同时保持人类细胞的完整性。虽然目前的研究很有见地,但仍处于早期阶段。为了充分发挥CMFs的治疗潜力,需要更全面的研究来完善其应用并确认其在不同临床情况下的有效性。这对于将CMFs整合到临床实践中至关重要,它们有望彻底改变治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complex Magnetic Fields: Harnessing the Electromagnetic Symphony for Possible Applications in Regenerative Medicine and Antifungal Properties

Complex magnetic fields (CMFs) represent an emerging frontier in regenerative medicine, offering significant potential for innovative therapeutic strategies. This review examined both the theoretical foundations and practical applications of CMFs, focusing on their roles in tissue regeneration and antifungal activity. A comprehensive review of electronic databases (PubMed, Scopus, and Embase) identified seven pivotal studies on in vitro models concerning the CMF topic. Although the number of studies is limited, they collectively highlighted the promising therapeutic potential of CMFs in enhancing wound healing, reducing oxidative stress, and neuroinflammation in diabetic neuropathy, positively influencing mitochondrial function, modulating immune responses, promoting cellular communication, inhibiting the growth and adhesion of Candida albicans to medical surfaces, and enhancing dental pulp stem cell proliferation under inflammatory conditions. These findings suggested that CMFs may offer an eco-sustainable approach, effectively targeting pathogens while preserving human cell integrity. While the current body of research is insightful, it remains in its early stages. To fully leverage the therapeutic potential of CMFs, more comprehensive studies are needed to refine their application and confirm their effectiveness across diverse clinical scenarios. This is essential for integrating CMFs into clinical practice, where they promise to revolutionise treatment approaches.

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来源期刊
International Wound Journal
International Wound Journal DERMATOLOGY-SURGERY
CiteScore
4.50
自引率
12.90%
发文量
266
审稿时长
6-12 weeks
期刊介绍: The Editors welcome papers on all aspects of prevention and treatment of wounds and associated conditions in the fields of surgery, dermatology, oncology, nursing, radiotherapy, physical therapy, occupational therapy and podiatry. The Journal accepts papers in the following categories: - Research papers - Review articles - Clinical studies - Letters - News and Views: international perspectives, education initiatives, guidelines and different activities of groups and societies. Calendar of events The Editors are supported by a board of international experts and a panel of reviewers across a range of disciplines and specialties which ensures only the most current and relevant research is published.
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