阿育吠陀治疗非酒精性脂肪性肝病合并肥胖和类风湿性关节炎1例

Q3 Pharmacology, Toxicology and Pharmaceutics

Phytomedicine Plus Pub Date : 2025-05-03 DOI:10.1016/j.phyplu.2025.100787

Amit Nakanekar, Rashmi Jaiswal

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引用次数: 0

摘要

背景：非酒精性脂肪性肝病（NAFLD）是慢性肝病的主要原因之一，全球发病率为25%。NAFLD的特点是复杂的“多打击”发病机制和疾病谱系。在阿育吠陀医学中，它被认为是“Yakrit vikar（∼肝病）”和“Medoroga（∼脂肪堆积引起的疾病）”。目的：52岁非酒精男性患者，在过去的6个月里，主述有腹胀、疲劳、虚弱、背部疼痛、双侧上肢刺痛、大腿和腹部出现条纹、双侧肩关节僵硬、厌食、便秘和种植区疼痛。患者被一所公立医学院收治，治疗II级脂肪肝，给予非甾体抗炎药、抗生素、抗酸药、类固醇和一些复合维生素片。然而，复发发生了，所以病人来到阿育吠陀同样的抱怨，所有关节都增加了疼痛。研究设计患者使用Santarpana（~过度消费和久坐不动的生活方式）和Krumighn Chikitsa（~旨在消除寄生虫的治疗）进行治疗。本病例的特点是克鲁米纳治疗NAFLD、类风湿关节炎和肥胖症效果良好。患者接受了4个月左右的Basti（用油和煎剂进行的药物灌肠）和阿育吠陀口服药物治疗。结果两组患者临床症状、体重、腹部及骨盆超声检查均有明显改善。结论必须进行进一步的研究以获得更多的科学证据来证明这种阿育吠陀方法的有效性。

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Ayurvedic management of non-alcoholic fatty liver disease with obesity and rheumatoid arthritis– A case report

Background

Non-alcoholic fatty Liver Disease (NAFLD) is one of the leading causes of chronic liver diseases, with a 25 % frequency worldwide. NAFLD is characterized by a complex "multi-hit" pathogenesis and spectrum of disorders. In Ayurveda, it is considered under Yakrit vikar (∼liver disease) with Medoroga (∼disease caused by excessive fat deposition).

Purpose

A 52-year-old non-alcoholic male patient came with complaints of abdominal distension, fatigue, weakness, back pain, bilateral upper limb tingling, striae present over the thigh and abdomen, bilateral shoulder joint stiffness, anorexia, constipation, and pain at the planter region for the last six months. The patient was admitted to a government medical college and was treated with NSAIDs, Antibiotics, antacids, steroids, and some multivitamin tablets for Grade II fatty liver disease. However, the recurrence occurred, so the patient came to Ayurveda for the same complaints with more added pain in all joints.

Study design

The patient was treated using Santarpana (∼overconsumption and sedentary lifestyle) and Krumighn Chikitsa (∼ treatment aimed at eliminating parasites). The specialty of this case is that Krumighna treatment worked well in NAFLD, rheumatoid arthritis, and obesity. The patient was treated for around four months with Basti (∼medicated enema using oil and decoction) and Ayurvedic oral medicines.