哺乳期心血管药物的安全性

IF 1.3 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Cristina Nunez-Pellot , Allison Akers , Sarah Običan , Mary Ashley Cain , Daniela R. Crousillat
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引用次数: 0

摘要

母乳喂养是婴儿喂养的黄金标准,具有公认的孕产妇、新生儿和儿科益处。既往存在心血管疾病的患者母乳喂养率低于一般人群。虽然很少有证据表明先前存在心血管疾病的患者的哺乳障碍,但对患有心血管疾病的母亲的哺乳安全性和药物暴露的担忧可能是早期停止母乳喂养的原因,尽管已知对健康有益。本文献综述强调了常见心脏药物的泌乳安全性。虽然一些常见的心脏药物的安全性数据可能有限,但哺乳期药物分泌的一般药代动力学原理可以帮助指导与患者讨论的共同决策。在母乳喂养期间加强提供者关于心脏药物安全的知识可能会改善这一人群的哺乳结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lactation safety of cardiovascular medications
Breastfeeding is the gold standard for infant feeding with well-established maternal, neonatal, and pediatric benefits. Patients with preexisting cardiovascular disease have lower breastfeeding rates than the general population. While little evidence exists regarding specific barriers to lactation in patients with preexisting cardiovascular disease, concerns regarding lactation safety and medication exposure in mothers with cardiovascular disease may be a cause for early breastfeeding cessation despite known health benefits. This literature review highlights the lactation safety of common cardiac medications. While some common cardiac medications may have limited safety data available, general pharmacokinetic principles of drug secretion in lactation can help to guide shared decision making in discussion with the patient. Enhancing provider knowledge regarding cardiac medication safety during breastfeeding may improve lactation outcomes in this population.
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来源期刊
CiteScore
1.60
自引率
0.00%
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59 days
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