1990-2021年全球、区域和国家各级常见性传播感染发病率趋势:《2021年全球疾病负担》研究结果。

IF 3.6 Q1 TROPICAL MEDICINE
Miao Deng, Jiaxi Chen, Zhi Wang, Rubin Zheng, Wenyi Pang, Rui Sun, Zhixun Bai
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引用次数: 0

摘要

背景:性传播疾病(STDs)在全球流行,是一项重大的公共卫生挑战。本研究旨在评估全球、区域和国家各级对常见性传播感染(sti)负担的最新估计,这将有助于制定更有效的预防战略。方法:本研究的数据通过全球健康数据交换(GHDx)查询工具(https://vizhub.healthdata.org/gbd-results/)从全球疾病负担(GBD) 2021研究中获得。我们根据GBD操作指南提取数据,选择了2021年GBD研究的最新结果。最新的GBD研究结果提供了21个地区和204个国家的发病率、患病率和残疾调整生命年(DALYs)数据。我们按照GBD使用指南,按性别、年龄组和地点提取了性传播疾病(STDs)的病例数、发病率和年龄标准化发病率。根据社会学人口学指数(sdi)将数据分为5类。结果:2021年性病患者总数约为28917万人,较1990年增长约58.38%。虽然男性的病例总数较高,但女性的增加更为明显。赤道几内亚梅毒年龄标准化率(ASR)最高(EAPC 0.57, 95% CI[- 2.97, 4.24])。坦桑尼亚毛滴虫病的ASR最高(EAPC - 1.24, 95% CI[- 4.97, 2.64])。南非淋球菌感染(EAPC - 0.52, 95% CI[- 4.33, 3.44])和衣原体感染(EAPC - 0.52, 95% CI[- 4.33, 3.44])的ASR最高,而津巴布韦生殖器疱疹感染(EAPC - 1.3, 95% CI[- 4.89, 2.44])的ASR最高。艾滋病毒/艾滋病的ASR在莱索托最高(EAPC - 0.33, 95% CI[- 3.99, 3.46]),艾滋病毒/艾滋病和性传播感染的ASR在南非最高(EAPC - 0.47, 95% CI[- 0.58, 0.37])。结论:性病负担居高不下,且呈持续上升趋势;性传播感染负担在低SDI地区和青壮年人群中更为严重;1990-2021年期间性传播感染的流行率、发病率和残疾调整年数可归因于三个主要因素:人口、疾病流行病学和老龄化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trends in the incidence of common sexually transmitted infections at the global, regional and national levels, 1990-2021: results of the Global Burden of Disease 2021 study.

Background: Sexually transmitted diseases (STDs) are prevalent globally and represent a significant public health challenge. This study aims to evaluate the most recent estimates of the burden of common sexually transmitted infections (STIs) at global, regional, and national levels, which will aid in the development of more effective prevention strategies.

Methods: Data for this study were obtained from the Global Burden of Disease (GBD) 2021 study via the Global Health Data Exchange (GHDx) query tool ( https://vizhub.healthdata.org/gbd-results/ ). We extracted the data in accordance with GBD operational guidelines, selecting the most recent results from the 2021 GBD study. The latest GBD study results provided data on incidence, prevalence, and disability-adjusted life years (DALYs) for 21 regions and 204 countries. We extracted the number of cases, incidence, and age-standardized incidence of sexually transmitted diseases (STDs) by sex, age group, and location, following GBD usage guidelines. The data were categorized into five groups based on sociological demographic indices (SDIs).

Results: In 2021, the total number of STDs was ~ 289.17 million, reflecting an increase of about 58.38% compared to 1990. While the total number of cases was higher in males, the increase was more pronounced in females. Syphilis exhibited the highest age-standardized rate (ASR) in Equatorial Guinea (EAPC 0.57, 95% CI [- 2.97, 4.24]). Trichomoniasis had the greatest ASR in Tanzania (EAPC - 1.24, 95% CI [- 4.97, 2.64]). Gonococcal (EAPC - 0.52, 95% CI [- 4.33, 3.44]) and chlamydial infections (EAPC - 0.52, 95% CI [- 4.33, 3.44]) showed the highest ASR in South Africa, while genital herpes (EAPC - 1.3, 95% CI [- 4.89, 2.44]) had the greatest ASR in Zimbabwe. HIV/AIDS had the highest ASR in Lesotho (EAPC - 0.33, 95% CI [- 3.99, 3.46]), and the combined ASR for HIV/AIDS and STIs was highest in South Africa (EAPC - 0.47, 95% CI [- 0.58, 0.37]).

Conclusion: The burden of STDs remains high and has been steadily increasing; the burden of STIs is more severe in low SDI areas and among young and middle-aged people; the prevalence, incidence, and disability-adjusted years of STIs during the period 1990-2021 are attributable to three main factors: population, disease epidemiology, and aging.

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来源期刊
Tropical Medicine and Health
Tropical Medicine and Health TROPICAL MEDICINE-
CiteScore
7.00
自引率
2.20%
发文量
90
审稿时长
11 weeks
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