手工治疗后颞下颌疾病（TMD）患者咬合关系的变化：一项初步研究

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research Pub Date : 2025-05-19 DOI:10.1002/cre2.70147

Tobias Dieter Peter Pohl, Alessia Celine Harhoff, Johannes Ries, Manfred Wichmann, Ragai-Edward Matta

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Occlusion measurements were obtained using the TRIOS 3 intraoral scanner (3Shape, Denmark) both before and after the therapy or control period. The digital models were analyzed regarding occlusal changes using the GOM Inspect Professional software (GOM, Germany). The differences in the individual axes <span></span><math>\n <semantics>\n <mrow>\n \n <mrow>\n <msub>\n <mi>dX</mi>\n \n <mi>Pat</mi>\n </msub>\n \n <mo>,</mo>\n \n <msub>\n <mi>dY</mi>\n \n <mi>Pat</mi>\n </msub>\n \n <mo>,</mo>\n \n <msub>\n <mi>dZ</mi>\n \n <mi>Pat</mi>\n </msub>\n \n <mo> </mo>\n \n <mrow>\n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n </mrow>\n </mrow>\n </mrow>\n <annotation> ${{dX}}_{{Pat}},{{dY}}_{{Pat}},{{dZ}}_{{Pat}}{\\unicode{x02007}}(\\mathrm{mm})$</annotation>\n </semantics></math> and Euclidean distance <span></span><math>\n <semantics>\n <mrow>\n \n <mrow>\n <msub>\n <mrow>\n <mi>d</mi>\n \n <mi>X</mi>\n \n <mi>Y</mi>\n \n <mi>Z</mi>\n </mrow>\n \n <mi>Pat</mi>\n </msub>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n </mrow>\n </mrow>\n <annotation> ${dXYZ}_{{Pat}}\\unicode{x02007}(\\mathrm{mm})$</annotation>\n </semantics></math> were computed.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>In terms of the arithmetic mean, Group MT exhibited higher deviations across all three axes (<span></span><math>\n <semantics>\n <mrow>\n \n <mrow>\n <msub>\n <mi>dX</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>M</mi>\n \n <mi>T</mi>\n </mrow>\n </msub>\n \n <mo>=</mo>\n \n <mn>0.122</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n \n <mo>,</mo>\n </mrow>\n \n <mrow>\n <msub>\n <mi>dY</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>M</mi>\n \n <mi>T</mi>\n </mrow>\n </msub>\n \n <mo>=</mo>\n \n <mn>0.217</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n \n <mo>,</mo>\n \n <mo> </mo>\n \n <msub>\n <mi>dZ</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>M</mi>\n \n <mi>T</mi>\n </mrow>\n </msub>\n <mspace></mspace>\n \n <mo>=</mo>\n <mspace></mspace>\n \n <mn>0.193</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n </mrow>\n </mrow>\n <annotation> ${{dX}}_{PatMT}=0.122\\unicode{x02007}(\\mathrm{mm}),{{dY}}_{PatMT}=0.217\\unicode{x02007}(\\mathrm{mm}),\\unicode{x02007}{{dZ}}_{PatMT}\\,=\\,0.193\\unicode{x02007}(\\mathrm{mm})$</annotation>\n </semantics></math>) as well as in the Euclidean distance <span></span><math>\n <semantics>\n <mrow>\n \n <mrow>\n <mo>(</mo>\n \n <mrow>\n <msub>\n <mrow>\n <mi>d</mi>\n \n <mi>X</mi>\n \n <mi>Y</mi>\n \n <mi>Z</mi>\n </mrow>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>M</mi>\n \n <mi>T</mi>\n </mrow>\n </msub>\n \n <mo>=</mo>\n \n <mn>0.347</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n </mrow>\n \n <mo>)</mo>\n </mrow>\n </mrow>\n <annotation> $({dXYZ}_{PatMT}=0.347\\unicode{x02007}(\\mathrm{mm}))$</annotation>\n </semantics></math> than the control group <span></span><math>\n <semantics>\n <mrow>\n \n <mrow>\n <mo>(</mo>\n \n <mrow>\n <mi>d</mi>\n \n <msub>\n <mi>X</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>C</mi>\n </mrow>\n </msub>\n \n <mo>=</mo>\n \n <mn>0.060</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n \n <mo>,</mo>\n \n <mo> </mo>\n \n <mi>d</mi>\n \n <msub>\n <mi>Y</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>C</mi>\n </mrow>\n </msub>\n \n <mo>=</mo>\n \n <mn>0.063</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n \n <mo>,</mo>\n \n <mo> </mo>\n \n <mi>d</mi>\n \n <msub>\n <mi>Z</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>C</mi>\n </mrow>\n </msub>\n <mspace></mspace>\n \n <mo>=</mo>\n <mspace></mspace>\n \n <mn>0.043</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n \n <mo>,</mo>\n \n <mo> </mo>\n \n <mi>d</mi>\n \n <mi>X</mi>\n \n <mi>Y</mi>\n \n <msub>\n <mi>Z</mi>\n \n <mrow>\n <mi>P</mi>\n \n <mi>a</mi>\n \n <mi>t</mi>\n \n <mi>C</mi>\n </mrow>\n </msub>\n \n <mo>=</mo>\n \n <mn>0.113</mn>\n \n <mo> </mo>\n \n <mo>(</mo>\n \n <mi>mm</mi>\n \n <mo>)</mo>\n </mrow>\n \n <mo>)</mo>\n </mrow>\n </mrow>\n <annotation> $(d{X}_{PatC}=0.060\\unicode{x02007}(\\mathrm{mm}),\\unicode{x02007}d{Y}_{PatC}=0.063\\unicode{x02007}(\\mathrm{mm}),\\unicode{x02007}d{Z}_{PatC}\\,=\\,0.043\\unicode{x02007}(\\mathrm{mm}),\\unicode{x02007}dXY{Z}_{PatC}=0.113\\unicode{x02007}(\\mathrm{mm}))$</annotation>\n </semantics></math>. Statistically significant differences were observed for the <i>Y</i> and <i>Z</i> axes, as well as the Euclidean distance (<i>p</i> < 0.05).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Considering the limitations of this pilot study, it is reasonable to suggest that manual therapy has a significant influence on occlusion in habitual intercuspidation among TMD patients.</p>\n </section>\n </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 3","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70147","citationCount":"0","resultStr":"{\"title\":\"Changes of the Occlusal Relationship in Patients With Temporomandibular Disorders (TMD) After Manual Therapy: A Pilot Study\",\"authors\":\"Tobias Dieter Peter Pohl, Alessia Celine Harhoff, Johannes Ries, Manfred Wichmann, Ragai-Edward Matta\",\"doi\":\"10.1002/cre2.70147\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>Temporomandibular disorders (TMD) are often linked to changes in dental occlusion, yet the impact of therapeutic interventions remains unclear. 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The differences in the individual axes <span></span><math>\\n <semantics>\\n <mrow>\\n \\n <mrow>\\n <msub>\\n <mi>dX</mi>\\n \\n <mi>Pat</mi>\\n </msub>\\n \\n <mo>,</mo>\\n \\n <msub>\\n <mi>dY</mi>\\n \\n <mi>Pat</mi>\\n </msub>\\n \\n <mo>,</mo>\\n \\n <msub>\\n <mi>dZ</mi>\\n \\n <mi>Pat</mi>\\n </msub>\\n \\n <mo> </mo>\\n \\n <mrow>\\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n </mrow>\\n </mrow>\\n </mrow>\\n <annotation> ${{dX}}_{{Pat}},{{dY}}_{{Pat}},{{dZ}}_{{Pat}}{\\\\unicode{x02007}}(\\\\mathrm{mm})$</annotation>\\n </semantics></math> and Euclidean distance <span></span><math>\\n <semantics>\\n <mrow>\\n \\n <mrow>\\n <msub>\\n <mrow>\\n <mi>d</mi>\\n \\n <mi>X</mi>\\n \\n <mi>Y</mi>\\n \\n <mi>Z</mi>\\n </mrow>\\n \\n <mi>Pat</mi>\\n </msub>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n </mrow>\\n </mrow>\\n <annotation> ${dXYZ}_{{Pat}}\\\\unicode{x02007}(\\\\mathrm{mm})$</annotation>\\n </semantics></math> were computed.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>In terms of the arithmetic mean, Group MT exhibited higher deviations across all three axes (<span></span><math>\\n <semantics>\\n <mrow>\\n \\n <mrow>\\n <msub>\\n <mi>dX</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>M</mi>\\n \\n <mi>T</mi>\\n </mrow>\\n </msub>\\n \\n <mo>=</mo>\\n \\n <mn>0.122</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n \\n <mo>,</mo>\\n </mrow>\\n \\n <mrow>\\n <msub>\\n <mi>dY</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>M</mi>\\n \\n <mi>T</mi>\\n </mrow>\\n </msub>\\n \\n <mo>=</mo>\\n \\n <mn>0.217</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n \\n <mo>,</mo>\\n \\n <mo> </mo>\\n \\n <msub>\\n <mi>dZ</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>M</mi>\\n \\n <mi>T</mi>\\n </mrow>\\n </msub>\\n <mspace></mspace>\\n \\n <mo>=</mo>\\n <mspace></mspace>\\n \\n <mn>0.193</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n </mrow>\\n </mrow>\\n <annotation> ${{dX}}_{PatMT}=0.122\\\\unicode{x02007}(\\\\mathrm{mm}),{{dY}}_{PatMT}=0.217\\\\unicode{x02007}(\\\\mathrm{mm}),\\\\unicode{x02007}{{dZ}}_{PatMT}\\\\,=\\\\,0.193\\\\unicode{x02007}(\\\\mathrm{mm})$</annotation>\\n </semantics></math>) as well as in the Euclidean distance <span></span><math>\\n <semantics>\\n <mrow>\\n \\n <mrow>\\n <mo>(</mo>\\n \\n <mrow>\\n <msub>\\n <mrow>\\n <mi>d</mi>\\n \\n <mi>X</mi>\\n \\n <mi>Y</mi>\\n \\n <mi>Z</mi>\\n </mrow>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>M</mi>\\n \\n <mi>T</mi>\\n </mrow>\\n </msub>\\n \\n <mo>=</mo>\\n \\n <mn>0.347</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n </mrow>\\n \\n <mo>)</mo>\\n </mrow>\\n </mrow>\\n <annotation> $({dXYZ}_{PatMT}=0.347\\\\unicode{x02007}(\\\\mathrm{mm}))$</annotation>\\n </semantics></math> than the control group <span></span><math>\\n <semantics>\\n <mrow>\\n \\n <mrow>\\n <mo>(</mo>\\n \\n <mrow>\\n <mi>d</mi>\\n \\n <msub>\\n <mi>X</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>C</mi>\\n </mrow>\\n </msub>\\n \\n <mo>=</mo>\\n \\n <mn>0.060</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n \\n <mo>,</mo>\\n \\n <mo> </mo>\\n \\n <mi>d</mi>\\n \\n <msub>\\n <mi>Y</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>C</mi>\\n </mrow>\\n </msub>\\n \\n <mo>=</mo>\\n \\n <mn>0.063</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n \\n <mo>,</mo>\\n \\n <mo> </mo>\\n \\n <mi>d</mi>\\n \\n <msub>\\n <mi>Z</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>C</mi>\\n </mrow>\\n </msub>\\n <mspace></mspace>\\n \\n <mo>=</mo>\\n <mspace></mspace>\\n \\n <mn>0.043</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n \\n <mo>,</mo>\\n \\n <mo> </mo>\\n \\n <mi>d</mi>\\n \\n <mi>X</mi>\\n \\n <mi>Y</mi>\\n \\n <msub>\\n <mi>Z</mi>\\n \\n <mrow>\\n <mi>P</mi>\\n \\n <mi>a</mi>\\n \\n <mi>t</mi>\\n \\n <mi>C</mi>\\n </mrow>\\n </msub>\\n \\n <mo>=</mo>\\n \\n <mn>0.113</mn>\\n \\n <mo> </mo>\\n \\n <mo>(</mo>\\n \\n <mi>mm</mi>\\n \\n <mo>)</mo>\\n </mrow>\\n \\n <mo>)</mo>\\n </mrow>\\n </mrow>\\n <annotation> $(d{X}_{PatC}=0.060\\\\unicode{x02007}(\\\\mathrm{mm}),\\\\unicode{x02007}d{Y}_{PatC}=0.063\\\\unicode{x02007}(\\\\mathrm{mm}),\\\\unicode{x02007}d{Z}_{PatC}\\\\,=\\\\,0.043\\\\unicode{x02007}(\\\\mathrm{mm}),\\\\unicode{x02007}dXY{Z}_{PatC}=0.113\\\\unicode{x02007}(\\\\mathrm{mm}))$</annotation>\\n </semantics></math>. Statistically significant differences were observed for the <i>Y</i> and <i>Z</i> axes, as well as the Euclidean distance (<i>p</i> < 0.05).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Considering the limitations of this pilot study, it is reasonable to suggest that manual therapy has a significant influence on occlusion in habitual intercuspidation among TMD patients.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10203,\"journal\":{\"name\":\"Clinical and Experimental Dental Research\",\"volume\":\"11 3\",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-05-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70147\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Dental Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/cre2.70147\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Dental Research","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cre2.70147","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

摘要

目的颞下颌紊乱（TMD）通常与牙合的改变有关，但治疗干预的影响尚不清楚。本初步研究通过口内扫描的定量分析来探讨手工治疗对TMD患者咬合的影响。材料和方法10例确诊为TMD的患者接受40分钟的手工治疗（MT组）。10名受试者被分配到健康对照组（C组），在10周的对照期内不接受任何治疗。在治疗前后或对照期使用TRIOS 3口内扫描仪（3Shape，丹麦）进行咬合测量。使用GOM Inspect Professional软件（GOM，德国）对咬合变化的数字模型进行分析。各轴dX的差，帕特先生，dZ帕特（mm）${{dX}}_{{Pat}},{{dY}}_{Pat}},{{dZ}}_{Pat}}{\unicode{x02007}}(\ maththrm {mm})$和欧几里得距离dXY Z Pat (mm)$ {dXYZ}_{{Pat}}\unicode{x02007}(\mathrm{mm})$被计算。就算术平均值而言，MT组在三个轴上均表现出较高的偏差（dX P at）M t = 0。 122 (mm)；dY P a t MT = 0.217 （mm）,dZ P a MT = 0.193 (mm)$ {{dX}}_{PatMT}=0.122\unicode{x02007}(\mathrm{mm}),{{dY}}_{PatMT}=0.217\unicode{x02007}（\mathrm{mm}),\unicode{x02007}{{dZ}}_{PatMT}\,=\,0.193\unicode{x02007}(\mathrm{mm})$）以及欧几里得距离(d X Y ZP a t M t =0.347 (mm))$ ({dXYZ} _ {PatMT} = 0。 347\unicode{x02007}(\mathrm{mm}))$比对照组(d XP = 0.060（mm）；d Y P at C = 0.063 (mm) ,d Z P at C = 0.043嗯)，d X Y Z Pa t C = 0。 113 (mm))$ (d {X} _ {PatC} = 0.060 \ unicode {x02007} (\ mathrm {mm}), unicode {x02007} \ d {Y} _ {PatC} = 0.063 \ unicode {x02007} (\ mathrm {mm}), unicode {x02007} \ d {Z} _ {PatC} \ = \ 0.043 \ unicode {x02007} (\ mathrm {mm}), unicode {x02007} \ dXY {Z} _ {PatC} = 0.113 \ unicode {x02007} (\ mathrm{毫米 }))$ .Y轴和Z轴以及欧氏距离的差异有统计学意义（p < 0.05）。结论考虑到本初步研究的局限性，我们有理由认为手工疗法对TMD患者习惯性牙间咬合有显著影响。

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Changes of the Occlusal Relationship in Patients With Temporomandibular Disorders (TMD) After Manual Therapy: A Pilot Study

Objectives

Temporomandibular disorders (TMD) are often linked to changes in dental occlusion, yet the impact of therapeutic interventions remains unclear. This pilot study investigates the effects of manual therapy on occlusion in TMD patients through quantitative analysis of intraoral scans.

Material and Methods

Ten individuals were diagnosed with TMD and underwent a 40-min session of manual therapy (Group MT). Ten subjects were allocated to the healthy control group (Group C) and did not receive any therapy during the 10-week control period. Occlusion measurements were obtained using the TRIOS 3 intraoral scanner (3Shape, Denmark) both before and after the therapy or control period. The digital models were analyzed regarding occlusal changes using the GOM Inspect Professional software (GOM, Germany). The differences in the individual axes ${dX}_{Pat}, {dY}_{Pat}, {dZ}_{Pat} (mm)$ and Euclidean distance ${d X Y Z}_{Pat} (mm)$ were computed.

Results

In terms of the arithmetic mean, Group MT exhibited higher deviations across all three axes ( ${dX}_{P a t M T} = 0.122 (mm), {dY}_{P a t M T} = 0.217 (mm), {dZ}_{P a t M T} = 0.193 (mm)$ ) as well as in the Euclidean distance $({d X Y Z}_{P a t M T} = 0.347 (mm))$ than the control group $(d X_{P a t C} = 0.060 (mm), d Y_{P a t C} = 0.063 (mm), d Z_{P a t C} = 0.043 (mm), d X Y Z_{P a t C} = 0.113 (mm))$ . Statistically significant differences were observed for the Y and Z axes, as well as the Euclidean distance (p < 0.05).

Conclusion

Considering the limitations of this pilot study, it is reasonable to suggest that manual therapy has a significant influence on occlusion in habitual intercuspidation among TMD patients.

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来源期刊

Clinical and Experimental Dental Research DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.30

自引率

5.60%

发文量

165

审稿时长

26 weeks

期刊介绍： Clinical and Experimental Dental Research aims to provide open access peer-reviewed publications of high scientific quality representing original clinical, diagnostic or experimental work within all disciplines and fields of oral medicine and dentistry. The scope of Clinical and Experimental Dental Research comprises original research material on the anatomy, physiology and pathology of oro-facial, oro-pharyngeal and maxillofacial tissues, and functions and dysfunctions within the stomatognathic system, and the epidemiology, aetiology, prevention, diagnosis, prognosis and therapy of diseases and conditions that have an effect on the homeostasis of the mouth, jaws, and closely associated structures, as well as the healing and regeneration and the clinical aspects of replacement of hard and soft tissues with biomaterials, and the rehabilitation of stomatognathic functions. Studies that bring new knowledge on how to advance health on the individual or public health levels, including interactions between oral and general health and ill-health are welcome.