Peter Gill , Mikkel Meyer Andersen , Jonathan P. Whitaker , Arnoud J. Kal , Walther Parson
{"title":"Birgitte Tengs案例:分析和对DNA证据评估的更广泛影响","authors":"Peter Gill , Mikkel Meyer Andersen , Jonathan P. Whitaker , Arnoud J. Kal , Walther Parson","doi":"10.1016/j.fsigen.2025.103279","DOIUrl":null,"url":null,"abstract":"<div><div>The Birgitte Tengs case was a high-profile investigation into an historic 1995 murder in Karmøy municipality, South East Norway. Rapidly mutating Y-STR analysis was carried out to identify a possible offender. The work was carried out over several years and involved a collaboration of four international laboratories. Based on the DNA evidence, in February, 2023, the defendant was convicted but later that year, he was exonerated on appeal. New investigations, resulting in new evidence, were carried out before the appeal. The new evidence gave alternative explanations for the presence of Y-STR in a stain that the conviction in the first trial relied heavily on.</div><div>Despite advanced techniques such as massively parallel sequencing and an extensive genealogy study encompassing Norway and beyond, the judgment revealed systemic issues, which included confirmation bias and reverse burden of proof. The case highlighted the critical importance of interpreting results according to the level at which propositions were made (e.g. sub-source or activity), as failure to do so could contribute to potential miscarriages of justice. Here, it is proposed that when there is no meaningful (specific) defence activity proposition identified, proxy experiments designed to maximise the probability of evidence supporting the defence alternative, will play an important role. Bayesian networks are useful methods to provide courts with lists of exhaustive methods of DNA transfer and has information illustrative properties. However, such networks can only help in actual probability computations if they can be populated with informative probabilities, and this can only happen if there is agreement on an experimental design to follow.</div><div>This paper examines the forensic methods, trial findings, and appeal court verdict, identifying areas where collaboration between scientist and court could improve decision-making. It proposes experimental designs and frameworks for enhancing activity-level evaluations, offering insights into minimising miscarriages of justice and better integrating forensic genetics into legal systems.</div></div>","PeriodicalId":50435,"journal":{"name":"Forensic Science International-Genetics","volume":"78 ","pages":"Article 103279"},"PeriodicalIF":3.2000,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Birgitte Tengs case: Analysis and the wider implications for evaluation of DNA evidence given activities\",\"authors\":\"Peter Gill , Mikkel Meyer Andersen , Jonathan P. Whitaker , Arnoud J. Kal , Walther Parson\",\"doi\":\"10.1016/j.fsigen.2025.103279\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The Birgitte Tengs case was a high-profile investigation into an historic 1995 murder in Karmøy municipality, South East Norway. Rapidly mutating Y-STR analysis was carried out to identify a possible offender. The work was carried out over several years and involved a collaboration of four international laboratories. Based on the DNA evidence, in February, 2023, the defendant was convicted but later that year, he was exonerated on appeal. New investigations, resulting in new evidence, were carried out before the appeal. The new evidence gave alternative explanations for the presence of Y-STR in a stain that the conviction in the first trial relied heavily on.</div><div>Despite advanced techniques such as massively parallel sequencing and an extensive genealogy study encompassing Norway and beyond, the judgment revealed systemic issues, which included confirmation bias and reverse burden of proof. The case highlighted the critical importance of interpreting results according to the level at which propositions were made (e.g. sub-source or activity), as failure to do so could contribute to potential miscarriages of justice. Here, it is proposed that when there is no meaningful (specific) defence activity proposition identified, proxy experiments designed to maximise the probability of evidence supporting the defence alternative, will play an important role. Bayesian networks are useful methods to provide courts with lists of exhaustive methods of DNA transfer and has information illustrative properties. However, such networks can only help in actual probability computations if they can be populated with informative probabilities, and this can only happen if there is agreement on an experimental design to follow.</div><div>This paper examines the forensic methods, trial findings, and appeal court verdict, identifying areas where collaboration between scientist and court could improve decision-making. It proposes experimental designs and frameworks for enhancing activity-level evaluations, offering insights into minimising miscarriages of justice and better integrating forensic genetics into legal systems.</div></div>\",\"PeriodicalId\":50435,\"journal\":{\"name\":\"Forensic Science International-Genetics\",\"volume\":\"78 \",\"pages\":\"Article 103279\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-04-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Forensic Science International-Genetics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1872497325000596\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GENETICS & HEREDITY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic Science International-Genetics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1872497325000596","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
Birgitte Tengs case: Analysis and the wider implications for evaluation of DNA evidence given activities
The Birgitte Tengs case was a high-profile investigation into an historic 1995 murder in Karmøy municipality, South East Norway. Rapidly mutating Y-STR analysis was carried out to identify a possible offender. The work was carried out over several years and involved a collaboration of four international laboratories. Based on the DNA evidence, in February, 2023, the defendant was convicted but later that year, he was exonerated on appeal. New investigations, resulting in new evidence, were carried out before the appeal. The new evidence gave alternative explanations for the presence of Y-STR in a stain that the conviction in the first trial relied heavily on.
Despite advanced techniques such as massively parallel sequencing and an extensive genealogy study encompassing Norway and beyond, the judgment revealed systemic issues, which included confirmation bias and reverse burden of proof. The case highlighted the critical importance of interpreting results according to the level at which propositions were made (e.g. sub-source or activity), as failure to do so could contribute to potential miscarriages of justice. Here, it is proposed that when there is no meaningful (specific) defence activity proposition identified, proxy experiments designed to maximise the probability of evidence supporting the defence alternative, will play an important role. Bayesian networks are useful methods to provide courts with lists of exhaustive methods of DNA transfer and has information illustrative properties. However, such networks can only help in actual probability computations if they can be populated with informative probabilities, and this can only happen if there is agreement on an experimental design to follow.
This paper examines the forensic methods, trial findings, and appeal court verdict, identifying areas where collaboration between scientist and court could improve decision-making. It proposes experimental designs and frameworks for enhancing activity-level evaluations, offering insights into minimising miscarriages of justice and better integrating forensic genetics into legal systems.
期刊介绍:
Forensic Science International: Genetics is the premier journal in the field of Forensic Genetics. This branch of Forensic Science can be defined as the application of genetics to human and non-human material (in the sense of a science with the purpose of studying inherited characteristics for the analysis of inter- and intra-specific variations in populations) for the resolution of legal conflicts.
The scope of the journal includes:
Forensic applications of human polymorphism.
Testing of paternity and other family relationships, immigration cases, typing of biological stains and tissues from criminal casework, identification of human remains by DNA testing methodologies.
Description of human polymorphisms of forensic interest, with special interest in DNA polymorphisms.
Autosomal DNA polymorphisms, mini- and microsatellites (or short tandem repeats, STRs), single nucleotide polymorphisms (SNPs), X and Y chromosome polymorphisms, mtDNA polymorphisms, and any other type of DNA variation with potential forensic applications.
Non-human DNA polymorphisms for crime scene investigation.
Population genetics of human polymorphisms of forensic interest.
Population data, especially from DNA polymorphisms of interest for the solution of forensic problems.
DNA typing methodologies and strategies.
Biostatistical methods in forensic genetics.
Evaluation of DNA evidence in forensic problems (such as paternity or immigration cases, criminal casework, identification), classical and new statistical approaches.
Standards in forensic genetics.
Recommendations of regulatory bodies concerning methods, markers, interpretation or strategies or proposals for procedural or technical standards.
Quality control.
Quality control and quality assurance strategies, proficiency testing for DNA typing methodologies.
Criminal DNA databases.
Technical, legal and statistical issues.
General ethical and legal issues related to forensic genetics.