Rong Yang, Liqin Gu, Chengzhou Li, Qiong Song, Yanfang Bao, Lan Lin, Juan Chen
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Small Cell Neuroendocrine Carcinoma of the Ureter: A Case Evaluated by 18FFDG- PET/CT and Literature Review.
Introduction: Small cell neuroendocrine carcinoma (SCNEC) of the ureter is extremely rare, and tends to show a mixed histologic profile. Literature on its imaging features is limited.
Case presentation: We herein report the case of a 68-year-old woman who presented with two days of left flank pain. Ultrasound and CT scan revealed a lesion in the left distal ureter. The lesion exhibited intensive tracer activity on 18F-FDG PET/CT scan, corresponding to a malignant tumor, most likely a high-grade urothelial carcinoma, and no metastases were observed. Then, the patient underwent a radical left nephroureterectomy. Pathology revealed a carcinoma composed of SCNEC (approximately 83%) and urothelial carcinoma (approximately 17%). During one year of follow-up, the patient underwent six cycles of adjuvant chemotherapy (etoposide 100mgd 1-3 + cisplatin 30mgd 1-3, q3w), and no recurrence or metastases were found on the CT scan.
Conclusion: This case report has presented a case of ureteral SCNEC and explored the value of 18F-FDG PET/CT in the diagnosis and staging of the disease.
期刊介绍：
Current Medical Imaging Reviews publishes frontier review articles, original research articles, drug clinical trial studies and guest edited thematic issues on all the latest advances on medical imaging dedicated to clinical research. All relevant areas are covered by the journal, including advances in the diagnosis, instrumentation and therapeutic applications related to all modern medical imaging techniques.
The journal is essential reading for all clinicians and researchers involved in medical imaging and diagnosis.
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