腰椎不同类型改变与骨密度的相关性研究。

IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Xiaoling Zhong, Yinghui Tang, Guohua Zeng, Lixiang Zhang, Minjie Yang, Yu Chen
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引用次数: 0

摘要

Modic changes (MCs)是腰椎退行性疾病的常见表现,分为三种类型。然而,骨密度(BMD)与椎体病变部位每种类型MC之间的关系尚不清楚。方法:本研究纳入144例腰部MR和CT影像。采用MR图像评价MCs的分类和分级。在CT图像上,从正常T12椎体、相应的腰椎modc病变部位以及同一椎体的相邻健康区域在轴向平面上获得BMD值、t评分和z评分。结果:共检查了370个椎体,其中MCs椎体226个,正常T12椎体144个。在本研究中,男性和女性正常T12椎体的骨密度无显著差异。MCs多见于腰椎4、5椎。其中80例(36%)为ⅰ型,130例(57%)为ⅱ型,16例(7%)为ⅲ型。各Modic型病变部位的BMD值、t评分、z评分均高于相邻健康区和正常T12椎体。不同的Modic类型之间存在很强的相关性,尽管在同一Modic类型内的年级之间没有观察到显着差异。结论:任何MCs的存在都与相应病变部位的BMD升高显著相关,且MCs越严重,BMD升高的相关性越强。这是第一个探讨所有类型MCs与其BMD值之间关系的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation Between Bone Mineral Density And Different Types of Modic Changes in Lumbar Spine.

Introduction: Modic changes (MCs) are a common manifestation of lumbar degenerative disease, classified into three types. However, the relationship between Bone Mineral Density (BMD) and each type of MC at the vertebral lesion sites remains unclear.

Methods: This study included 144 patients who had both lumbar MR and CT images. The classification and grading of MCs were evaluated using MR images. On the CT images, BMD values, T-scores, and Z-scores were obtained from the normal T12 vertebrae, the corresponding lumbar Modic lesion sites, and the adjacent healthy regions at the same vertebra on the axial plane.

Results: A total of 370 vertebrae (226 MCs and 144 normal T12 vertebrae) were assessed. No significant difference was found in the BMD of normal T12 vertebrae between males and females in the study. MCs were more commonly found in the lumbar 4 and 5 vertebrae. Of the MCs, 80 (36%) were classified as type I, 130 (57%) as type II, and 16 (7%) as type III. The BMD value, T-score, and Z-score of each Modic type lesion site were higher than those of adjacent healthy regions and normal T12 vertebrae. A strong correlation was found between the different Modic types, though no significant differences were observed between grades within the same Modic type.

Conclusion: The presence of any MCs was significantly associated with an increase in BMD in the corresponding lesion sites, with more severe MCs showing a stronger association with higher BMD. This is the first study to explore the relationship between all types of MCs and their BMD values.

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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
246
审稿时长
1 months
期刊介绍: Current Medical Imaging Reviews publishes frontier review articles, original research articles, drug clinical trial studies and guest edited thematic issues on all the latest advances on medical imaging dedicated to clinical research. All relevant areas are covered by the journal, including advances in the diagnosis, instrumentation and therapeutic applications related to all modern medical imaging techniques. The journal is essential reading for all clinicians and researchers involved in medical imaging and diagnosis.
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