{"title":"绘制疫苗创新中人工智能和机器学习的景观:一项文献计量学研究。","authors":"Jirui Niu, Ruotian Deng, Zipu Dong, Xue Yang, Zhaohui Xing, Yin Yu, Jian Kang","doi":"10.1080/21645515.2025.2501358","DOIUrl":null,"url":null,"abstract":"<p><p>With the rapid advancement of artificial intelligence (AI) and machine learning (ML) technologies, their applications in the medical field have expanded significantly. Particularly in vaccine innovation, AI and ML have shown considerable potential. This article employs bibliometric analysis to examine the progress of AI and ML in vaccine innovation over recent years. By conducting literature retrieval, data extraction, and intelligent analysis through Web of Science, it provides more accurate and comprehensive insights into vaccine development and dosimetry. The rapid growth in research publications since 2012, particularly the geometric growth observed since 2017, underscores the increasing recognition of the potential of AI and ML to revolutionize vaccine development. However, despite the substantial benefits of AI and ML in vaccine innovation, challenges remain regarding data quality, algorithm reliability, and ethical considerations. As technology continues to advance and research deepens, AI and machine learning are anticipated to play an even more pivotal role in vaccine innovation. Notably, AI has the potential to accelerate vaccine development timelines, particularly in the context of emerging infectious diseases. By leveraging data-driven insights and predictive modeling, AI can streamline processes such as antigen discovery, clinical trial design, and risk assessment, thereby enabling faster responses to public health emergencies. This capability is especially critical for addressing sudden outbreaks of infectious diseases, where rapid deployment of effective vaccines can significantly mitigate global health risks.</p>","PeriodicalId":49067,"journal":{"name":"Human Vaccines & Immunotherapeutics","volume":"21 1","pages":"2501358"},"PeriodicalIF":3.5000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087483/pdf/","citationCount":"0","resultStr":"{\"title\":\"Mapping the landscape of AI and ML in vaccine innovation: A bibliometric study.\",\"authors\":\"Jirui Niu, Ruotian Deng, Zipu Dong, Xue Yang, Zhaohui Xing, Yin Yu, Jian Kang\",\"doi\":\"10.1080/21645515.2025.2501358\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>With the rapid advancement of artificial intelligence (AI) and machine learning (ML) technologies, their applications in the medical field have expanded significantly. 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Notably, AI has the potential to accelerate vaccine development timelines, particularly in the context of emerging infectious diseases. By leveraging data-driven insights and predictive modeling, AI can streamline processes such as antigen discovery, clinical trial design, and risk assessment, thereby enabling faster responses to public health emergencies. 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引用次数: 0
摘要
随着人工智能(AI)和机器学习(ML)技术的快速发展,它们在医疗领域的应用已经显著扩大。特别是在疫苗创新方面,人工智能和机器学习显示出相当大的潜力。本文采用文献计量学分析来考察近年来人工智能和机器学习在疫苗创新方面的进展。通过Web of Science进行文献检索、数据提取和智能分析,为疫苗开发和剂量学提供更准确、更全面的见解。自2012年以来,研究出版物的快速增长,特别是自2017年以来观察到的几何增长,突显出人们越来越认识到人工智能和机器学习在彻底改变疫苗开发方面的潜力。然而,尽管人工智能和机器学习在疫苗创新方面带来了巨大的好处,但在数据质量、算法可靠性和伦理考虑方面仍然存在挑战。随着技术的不断进步和研究的深入,预计人工智能和机器学习将在疫苗创新中发挥更加关键的作用。值得注意的是,人工智能有可能加快疫苗开发时间表,特别是在新出现传染病的情况下。通过利用数据驱动的洞察力和预测建模,人工智能可以简化抗原发现、临床试验设计和风险评估等流程,从而能够更快地应对突发公共卫生事件。这种能力对于应对传染病的突然爆发尤其重要,在这种情况下,快速部署有效的疫苗可以大大减轻全球健康风险。
Mapping the landscape of AI and ML in vaccine innovation: A bibliometric study.
With the rapid advancement of artificial intelligence (AI) and machine learning (ML) technologies, their applications in the medical field have expanded significantly. Particularly in vaccine innovation, AI and ML have shown considerable potential. This article employs bibliometric analysis to examine the progress of AI and ML in vaccine innovation over recent years. By conducting literature retrieval, data extraction, and intelligent analysis through Web of Science, it provides more accurate and comprehensive insights into vaccine development and dosimetry. The rapid growth in research publications since 2012, particularly the geometric growth observed since 2017, underscores the increasing recognition of the potential of AI and ML to revolutionize vaccine development. However, despite the substantial benefits of AI and ML in vaccine innovation, challenges remain regarding data quality, algorithm reliability, and ethical considerations. As technology continues to advance and research deepens, AI and machine learning are anticipated to play an even more pivotal role in vaccine innovation. Notably, AI has the potential to accelerate vaccine development timelines, particularly in the context of emerging infectious diseases. By leveraging data-driven insights and predictive modeling, AI can streamline processes such as antigen discovery, clinical trial design, and risk assessment, thereby enabling faster responses to public health emergencies. This capability is especially critical for addressing sudden outbreaks of infectious diseases, where rapid deployment of effective vaccines can significantly mitigate global health risks.
期刊介绍:
(formerly Human Vaccines; issn 1554-8619)
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics.
Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.