{"title":"甲状腺结节患者心理健康状况的横断面研究","authors":"Peng Wang, Jing Yan, Honghai He, Ying Che","doi":"10.2147/JMDH.S513795","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the mental health status of patients with high-risk and low-risk thyroid nodules (TNs), and the potential psychological risk factors that may exist in patients with high-risk nodules.</p><p><strong>Patients and methods: </strong>In this cross-sectional study, a total of 7645 adults who participated in physical examinations from January 2021 to December 2023 were included. During the physical examination, they all completed thyroid ultrasound examinations and laboratory tests, and filled out self-administered questionnaires, as well as the Symptom Checklist-90 (SCL-90) and the Stress Self-Assessment Questionnaire-53 (SSQ-53). These were used to collect general information, mental health status, and stress levels of the subjects. According to the degree of malignant risk, TNs were categorized into high-risk groups (HRG) and low-risk groups (LRG). Differences between the two groups were compared in terms of general information, mental health status scores, and laboratory indicators.</p><p><strong>Results: </strong>The overall detection rate of TNs was 34.5%, with a significantly higher rate in women. There were significant differences in age and gender between HRG and LRG; The total score of SCL-90 in the HRG was significantly higher than that in LRG (128.78±45.65 vs 120.59±31.68, p=0.044); HRG exhibited a higher proportion of positive rates in the somatization (P=0.033) and anxiety (P=0.048) factors of the SCL-90. Among the 10 factors of SCL-90, the scores of somatization (P=0.011), obsessive-compulsive (P=0.010), interpersonal sensitivity (P=0.032), depression (P=0.036) and additional factors (diet and sleep) (P=0.008) in HRG were significantly higher. The results of SSQ-53 suggest that the overall stress level in HRG is higher, and the cognitive stress is significantly higher than that in LRG (P=0.003). Multivariate logistic regression analysis showed that age, gender, and SCL-90 total score were risk factors for high-risk TNs.</p><p><strong>Conclusion: </strong>High-risk TNs are more common in females and older adults. The existence of high-risk TNs is related to poor mental health status.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"2641-2650"},"PeriodicalIF":2.7000,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075463/pdf/","citationCount":"0","resultStr":"{\"title\":\"Mental Health Status of Patients with Thyroid Nodules: A Cross-Sectional Study.\",\"authors\":\"Peng Wang, Jing Yan, Honghai He, Ying Che\",\"doi\":\"10.2147/JMDH.S513795\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aims to investigate the mental health status of patients with high-risk and low-risk thyroid nodules (TNs), and the potential psychological risk factors that may exist in patients with high-risk nodules.</p><p><strong>Patients and methods: </strong>In this cross-sectional study, a total of 7645 adults who participated in physical examinations from January 2021 to December 2023 were included. During the physical examination, they all completed thyroid ultrasound examinations and laboratory tests, and filled out self-administered questionnaires, as well as the Symptom Checklist-90 (SCL-90) and the Stress Self-Assessment Questionnaire-53 (SSQ-53). These were used to collect general information, mental health status, and stress levels of the subjects. According to the degree of malignant risk, TNs were categorized into high-risk groups (HRG) and low-risk groups (LRG). Differences between the two groups were compared in terms of general information, mental health status scores, and laboratory indicators.</p><p><strong>Results: </strong>The overall detection rate of TNs was 34.5%, with a significantly higher rate in women. There were significant differences in age and gender between HRG and LRG; The total score of SCL-90 in the HRG was significantly higher than that in LRG (128.78±45.65 vs 120.59±31.68, p=0.044); HRG exhibited a higher proportion of positive rates in the somatization (P=0.033) and anxiety (P=0.048) factors of the SCL-90. Among the 10 factors of SCL-90, the scores of somatization (P=0.011), obsessive-compulsive (P=0.010), interpersonal sensitivity (P=0.032), depression (P=0.036) and additional factors (diet and sleep) (P=0.008) in HRG were significantly higher. The results of SSQ-53 suggest that the overall stress level in HRG is higher, and the cognitive stress is significantly higher than that in LRG (P=0.003). Multivariate logistic regression analysis showed that age, gender, and SCL-90 total score were risk factors for high-risk TNs.</p><p><strong>Conclusion: </strong>High-risk TNs are more common in females and older adults. The existence of high-risk TNs is related to poor mental health status.</p>\",\"PeriodicalId\":16357,\"journal\":{\"name\":\"Journal of Multidisciplinary Healthcare\",\"volume\":\"18 \",\"pages\":\"2641-2650\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075463/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Multidisciplinary Healthcare\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/JMDH.S513795\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Multidisciplinary Healthcare","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/JMDH.S513795","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
摘要
目的：探讨高危和低危甲状腺结节（TNs）患者的心理健康状况，以及高危结节患者可能存在的潜在心理危险因素。患者和方法：在本横断面研究中，共纳入了2021年1月至2023年12月参加体检的7645名成年人。体格检查期间，所有患者均完成甲状腺超声检查和实验室检查，并填写自填问卷、症状量表-90 （SCL-90）和压力自评问卷-53 （SSQ-53）。这些数据用于收集受试者的一般信息、心理健康状况和压力水平。根据恶性危险程度将tnn分为高危组（HRG）和低危组（LRG）。比较两组在一般信息、心理健康状况评分和实验室指标方面的差异。结果：TNs总检出率为34.5%，其中女性检出率明显高于女性。HRG组与LRG组在年龄、性别上存在显著差异；HRG组SCL-90总分显著高于LRG组（128.78±45.65 vs 120.59±31.68,p=0.044）；在SCL-90的躯体化因子（P=0.033）和焦虑因子（P=0.048）中，HRG的阳性率较高。其中，躯体化（P=0.011）、强迫（P=0.010）、人际敏感（P=0.032）、抑郁（P=0.036）和附加因素（饮食和睡眠）（P=0.008）得分显著高于其他因素（P=0.008）。SSQ-53结果显示，HRG组整体应激水平较高，认知应激显著高于LRG组（P=0.003）。多因素logistic回归分析显示，年龄、性别、SCL-90总分是高危TNs的危险因素。结论：高危TNs多见于女性和老年人。高危神经痛的存在与不良的心理健康状况有关。
Mental Health Status of Patients with Thyroid Nodules: A Cross-Sectional Study.
Purpose: This study aims to investigate the mental health status of patients with high-risk and low-risk thyroid nodules (TNs), and the potential psychological risk factors that may exist in patients with high-risk nodules.
Patients and methods: In this cross-sectional study, a total of 7645 adults who participated in physical examinations from January 2021 to December 2023 were included. During the physical examination, they all completed thyroid ultrasound examinations and laboratory tests, and filled out self-administered questionnaires, as well as the Symptom Checklist-90 (SCL-90) and the Stress Self-Assessment Questionnaire-53 (SSQ-53). These were used to collect general information, mental health status, and stress levels of the subjects. According to the degree of malignant risk, TNs were categorized into high-risk groups (HRG) and low-risk groups (LRG). Differences between the two groups were compared in terms of general information, mental health status scores, and laboratory indicators.
Results: The overall detection rate of TNs was 34.5%, with a significantly higher rate in women. There were significant differences in age and gender between HRG and LRG; The total score of SCL-90 in the HRG was significantly higher than that in LRG (128.78±45.65 vs 120.59±31.68, p=0.044); HRG exhibited a higher proportion of positive rates in the somatization (P=0.033) and anxiety (P=0.048) factors of the SCL-90. Among the 10 factors of SCL-90, the scores of somatization (P=0.011), obsessive-compulsive (P=0.010), interpersonal sensitivity (P=0.032), depression (P=0.036) and additional factors (diet and sleep) (P=0.008) in HRG were significantly higher. The results of SSQ-53 suggest that the overall stress level in HRG is higher, and the cognitive stress is significantly higher than that in LRG (P=0.003). Multivariate logistic regression analysis showed that age, gender, and SCL-90 total score were risk factors for high-risk TNs.
Conclusion: High-risk TNs are more common in females and older adults. The existence of high-risk TNs is related to poor mental health status.
期刊介绍：
The Journal of Multidisciplinary Healthcare (JMDH) aims to represent and publish research in healthcare areas delivered by practitioners of different disciplines. This includes studies and reviews conducted by multidisciplinary teams as well as research which evaluates or reports the results or conduct of such teams or healthcare processes in general. The journal covers a very wide range of areas and we welcome submissions from practitioners at all levels and from all over the world. Good healthcare is not bounded by person, place or time and the journal aims to reflect this. The JMDH is published as an open-access journal to allow this wide range of practical, patient relevant research to be immediately available to practitioners who can access and use it immediately upon publication.
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