{"title":"舌下使用阿托品滴眼液治疗氯氮平引起的唾液漏。","authors":"Anirban Saha, Ayush Singh, Neethu K Nandan, Shrayasi Das, Aditya Somani","doi":"10.4103/ipj.ipj_352_24","DOIUrl":null,"url":null,"abstract":"<p><p>Clozapine is the drug of choice for patients with treatment-resistant schizophrenia. However, it has a variety of adverse effects. Sialorrhea is a bothersome side effect that can have an impact on both medical and psychosocial aspects. There is limited literature on the use of 1% atropine eye drops sublingually for the treatment of clozapine-induced sialorrhea (CIS). In this case series, we report three patients of CIS treated successfully with 1% atropine eye drops given sublingually.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"123-125"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077623/pdf/","citationCount":"0","resultStr":"{\"title\":\"Sublingual use of atropine eye drops for the treatment of clozapine induced sialorrhea.\",\"authors\":\"Anirban Saha, Ayush Singh, Neethu K Nandan, Shrayasi Das, Aditya Somani\",\"doi\":\"10.4103/ipj.ipj_352_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Clozapine is the drug of choice for patients with treatment-resistant schizophrenia. However, it has a variety of adverse effects. Sialorrhea is a bothersome side effect that can have an impact on both medical and psychosocial aspects. There is limited literature on the use of 1% atropine eye drops sublingually for the treatment of clozapine-induced sialorrhea (CIS). In this case series, we report three patients of CIS treated successfully with 1% atropine eye drops given sublingually.</p>\",\"PeriodicalId\":13534,\"journal\":{\"name\":\"Industrial Psychiatry Journal\",\"volume\":\"34 1\",\"pages\":\"123-125\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077623/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Industrial Psychiatry Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ipj.ipj_352_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Industrial Psychiatry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ipj.ipj_352_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/15 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Sublingual use of atropine eye drops for the treatment of clozapine induced sialorrhea.
Clozapine is the drug of choice for patients with treatment-resistant schizophrenia. However, it has a variety of adverse effects. Sialorrhea is a bothersome side effect that can have an impact on both medical and psychosocial aspects. There is limited literature on the use of 1% atropine eye drops sublingually for the treatment of clozapine-induced sialorrhea (CIS). In this case series, we report three patients of CIS treated successfully with 1% atropine eye drops given sublingually.
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