Simon D Archambault, Omar Abu-Qamar, David Biery, Antonio Yaghy, Brittany Weber, Nadia K Waheed
{"title":"视网膜光学相干断层扫描血管造影(OCTA)心血管疾病的生物标志物:综述文章。","authors":"Simon D Archambault, Omar Abu-Qamar, David Biery, Antonio Yaghy, Brittany Weber, Nadia K Waheed","doi":"10.1038/s41433-025-03780-8","DOIUrl":null,"url":null,"abstract":"<p><p>This review article systematically assesses existing literature on studies employing retinal optical coherence tomography angiography (OCTA) metrics as surrogate biomarkers for cardiovascular disease. A comprehensive, literature review of published peer-reviewed research was conducted within PubMed utilizing the following medical subject headings (MeSH) terms: \"optical coherence tomography\", \"cardiovascular diseases\", \"retina\", and \"retinal vessels\". A total of 840 articles were reviewed and selectively filtered with ultimately 50 articles being included. This review article elucidates key findings, identifies limitations, and pinpoints gaps within these investigations. Additionally, this article delineates constraints related to OCTA technology and image processing that presently hinder the widespread adoption of this promising technology.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Retinal optical coherence tomography angiography (OCTA) biomarkers of cardiovascular disease: a review article.\",\"authors\":\"Simon D Archambault, Omar Abu-Qamar, David Biery, Antonio Yaghy, Brittany Weber, Nadia K Waheed\",\"doi\":\"10.1038/s41433-025-03780-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This review article systematically assesses existing literature on studies employing retinal optical coherence tomography angiography (OCTA) metrics as surrogate biomarkers for cardiovascular disease. A comprehensive, literature review of published peer-reviewed research was conducted within PubMed utilizing the following medical subject headings (MeSH) terms: \\\"optical coherence tomography\\\", \\\"cardiovascular diseases\\\", \\\"retina\\\", and \\\"retinal vessels\\\". A total of 840 articles were reviewed and selectively filtered with ultimately 50 articles being included. This review article elucidates key findings, identifies limitations, and pinpoints gaps within these investigations. Additionally, this article delineates constraints related to OCTA technology and image processing that presently hinder the widespread adoption of this promising technology.</p>\",\"PeriodicalId\":12125,\"journal\":{\"name\":\"Eye\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-05-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eye\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41433-025-03780-8\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eye","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41433-025-03780-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Retinal optical coherence tomography angiography (OCTA) biomarkers of cardiovascular disease: a review article.
This review article systematically assesses existing literature on studies employing retinal optical coherence tomography angiography (OCTA) metrics as surrogate biomarkers for cardiovascular disease. A comprehensive, literature review of published peer-reviewed research was conducted within PubMed utilizing the following medical subject headings (MeSH) terms: "optical coherence tomography", "cardiovascular diseases", "retina", and "retinal vessels". A total of 840 articles were reviewed and selectively filtered with ultimately 50 articles being included. This review article elucidates key findings, identifies limitations, and pinpoints gaps within these investigations. Additionally, this article delineates constraints related to OCTA technology and image processing that presently hinder the widespread adoption of this promising technology.
期刊介绍:
Eye seeks to provide the international practising ophthalmologist with high quality articles, of academic rigour, on the latest global clinical and laboratory based research. Its core aim is to advance the science and practice of ophthalmology with the latest clinical- and scientific-based research. Whilst principally aimed at the practising clinician, the journal contains material of interest to a wider readership including optometrists, orthoptists, other health care professionals and research workers in all aspects of the field of visual science worldwide. Eye is the official journal of The Royal College of Ophthalmologists.
Eye encourages the submission of original articles covering all aspects of ophthalmology including: external eye disease; oculo-plastic surgery; orbital and lacrimal disease; ocular surface and corneal disorders; paediatric ophthalmology and strabismus; glaucoma; medical and surgical retina; neuro-ophthalmology; cataract and refractive surgery; ocular oncology; ophthalmic pathology; ophthalmic genetics.