揭示细胞信号的生物物理学。

IF 4.9 Q1 BIOPHYSICS

Biophysical reviews Pub Date : 2025-04-10 eCollection Date: 2025-04-01 DOI:10.1007/s12551-025-01308-8

Silvina Ponce Dawson

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引用次数: 0

摘要

在这篇报告中，我描述了我们在过去25年中使用生物物理学工具在细胞信号传导领域所解决的一些主题和问题。该报告涵盖了我们在细胞内ca2 +信号、模式形成、细胞内部信使的运输、实验中生物物理参数的量化和信息传递方面的部分工作。描述包括我们的建模和实验工作，强调物理工具如何能够为生物系统的工作提供有用的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biological physics to uncover cell signaling.

In this report, I describe some of the subjects and problems that we have addressed over the last 25 years in the area of cell signaling using the tools of biological physics. The report covers part of our work on intracellular Ca $^{2 +}$ signals, pattern formation, transport of messengers in the interior of cells, quantification of biophysical parameters from experiments, and information transmission. The description includes both our modeling and experimental work highlighting how the tools of physics can give useful insights into the workings of biological systems.

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来源期刊

Biophysical reviews Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

8.90

自引率

0.00%

发文量

期刊介绍： Biophysical Reviews aims to publish critical and timely reviews from key figures in the field of biophysics. The bulk of the reviews that are currently published are from invited authors, but the journal is also open for non-solicited reviews. Interested authors are encouraged to discuss the possibility of contributing a review with the Editor-in-Chief prior to submission. Through publishing reviews on biophysics, the editors of the journal hope to illustrate the great power and potential of physical techniques in the biological sciences, they aim to stimulate the discussion and promote further research and would like to educate and enthuse basic researcher scientists and students of biophysics. Biophysical Reviews covers the entire field of biophysics, generally defined as the science of describing and defining biological phenomenon using the concepts and the techniques of physics. This includes but is not limited by such areas as: - Bioinformatics - Biophysical methods and instrumentation - Medical biophysics - Biosystems - Cell biophysics and organization - Macromolecules: dynamics, structures and interactions - Single molecule biophysics - Membrane biophysics, channels and transportation