铜催化叠氮系碘酰化物合成C-2取代吲哚林-3- 1和吲哚林-3- 1[4+2]环加合物[j]。化学5/2025)

IF 2.8 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2025-05-15 DOI:10.1002/ajoc.202580502

Israel Najar Guerrero, Zinah Al-Khateeb, Prof. F. G. West

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引用次数: 0

摘要

容易形成的碘化物被铜催化剂迅速消耗。邻叠氮基的存在使得在失去分子氮的情况下形成新的C=N键，实际上耦合了两个亲核中心。这些反应性的c -酰基胺可以被各种亲核试剂或1,3-二烯捕获以获得吲哚-3- 1产物。更多细节可以在Israel Najar Guerrero， zina Al-Khateeb和Frederick G. West的文章e202400612中找到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cover Feature: Copper-Catalyzed Synthesis of C-2 Substituted Indolin-3-Ones and Indolin-3-One [4+2] Cycloadducts Through Azide-Tethered Iodonium Ylides (Asian J. Org. Chem. 5/2025)

Easily formed iodonium ylides are rapidly consumed by copper catalysts. The presence of an ortho-azido group allows formation of a new C=N bond with loss of molecular nitrogen, in effect coupling two nucleophilic centers. These reactive C-acylimines can be captured with a variety of nucleophiles or 1,3-dienes to afford indolin-3-one products. More details can be found in article number e202400612 by Israel Najar Guerrero, Zinah Al-Khateeb, and Frederick G. West.

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.