用于ph控制药物释放和环境传感的多功能荧光β-环糊精水凝胶

IF 4.7 3区工程技术 Q2 ENGINEERING, ENVIRONMENTAL

Journal of Polymers and the Environment Pub Date : 2025-04-26 DOI:10.1007/s10924-025-03574-9

Swati Thakur, Sapna Sethi, Narveer Singh, Akshay Kumar

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引用次数: 0

摘要

利用自由基聚合反应合成了一种生物可降解、生物兼容的荧光β-环糊精水凝胶，用于先进的药物递送。该水凝胶对双氯芬酸钠具有控释和缓释作用，提高了生物利用度，延长了药物吸收。β-环糊精水凝胶的固有荧光使双氯芬酸钠在水环境中的监测成为可能，使其成为药物递送和传感应用的双重功能系统。

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Multifunctional Fluorescent β-cyclodextrin Hydrogel for pH-controlled Drug Release and Environmental Sensing

Highlights

A biodegradable and biocompatible fluorescent β-cyclodextrin hydrogel was synthesized using a free radical polymerization reaction for advanced drug delivery applications.
The hydrogel demonstrated controlled and sustained release of diclofenac sodium, enhancing bioavailability and extending drug absorption.
The intrinsic fluorescence of the β-cyclodextrin hydrogel enables the monitoring of diclofenac sodium in an aqueous environment, making it a dual-functional system for drug delivery and sensing applications.

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来源期刊

Journal of Polymers and the Environment 工程技术-高分子科学

CiteScore

9.50

自引率

7.50%

发文量

297

审稿时长

9 months

期刊介绍： The Journal of Polymers and the Environment fills the need for an international forum in this diverse and rapidly expanding field. The journal serves a crucial role for the publication of information from a wide range of disciplines and is a central outlet for the publication of high-quality peer-reviewed original papers, review articles and short communications. The journal is intentionally interdisciplinary in regard to contributions and covers the following subjects - polymers, environmentally degradable polymers, and degradation pathways: biological, photochemical, oxidative and hydrolytic; new environmental materials: derived by chemical and biosynthetic routes; environmental blends and composites; developments in processing and reactive processing of environmental polymers; characterization of environmental materials: mechanical, physical, thermal, rheological, morphological, and others; recyclable polymers and plastics recycling environmental testing: in-laboratory simulations, outdoor exposures, and standardization of methodologies; environmental fate: end products and intermediates of biodegradation; microbiology and enzymology of polymer biodegradation; solid-waste management and public legislation specific to environmental polymers; and other related topics.