{"title":"生物传感器用铝掺杂ZnO纳米棒的制备与表征","authors":"Hsin-Yu Chou;Yu-Wei Chen;Chang-Tze Ricky Yu;Jo-Mei Maureen Chen;Wei-Hsiang Chiang;Anoop Kumar Singh;Po-Kai Kung;Jung-Lung Chiang;Dong-Sing Wuu","doi":"10.1109/JSEN.2025.3552595","DOIUrl":null,"url":null,"abstract":"In this study, we prepared various aluminum-doped zinc oxide (AZO) surface structures via chemical bath deposition (CBD) for use in biomedical sensors. Indium tin oxide (ITO) conductive films were deposited on glass substrates via electron beam evaporation, and AZO nanorods were subsequently grown on the ITO layer using CBD at a bath temperature of <inline-formula> <tex-math>$90~^{\\circ }$ </tex-math></inline-formula>C. The AZO/ITO sensor electrode was further optimized through furnace annealing, improving its structural and electrical properties. This nanostructure enhances the ability of biomedical sensor films to adsorb H+ and OH<inline-formula> <tex-math>${}^{-}$ </tex-math></inline-formula> ions by increasing the reactive surface area between the film and the solution under test, thereby improving pH sensitivity. In addition, we used an extended gate field effect transistor (EGFET) module to measure glucose concentrations ranging from 0 to 10 mg/ml, achieving sensitivity values of 55.4 mV/pH and 8.07 mA/mg<inline-formula> <tex-math>$\\cdot $ </tex-math></inline-formula>ml<inline-formula> <tex-math>${}^{-{1}}$ </tex-math></inline-formula>. These findings have significant implications for the future development of blood glucose monitoring and microenvironmental sensing systems.","PeriodicalId":447,"journal":{"name":"IEEE Sensors Journal","volume":"25 10","pages":"16648-16657"},"PeriodicalIF":4.3000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fabrication and Characterization of Aluminum-Doped ZnO Nanorods for Biosensor Applications\",\"authors\":\"Hsin-Yu Chou;Yu-Wei Chen;Chang-Tze Ricky Yu;Jo-Mei Maureen Chen;Wei-Hsiang Chiang;Anoop Kumar Singh;Po-Kai Kung;Jung-Lung Chiang;Dong-Sing Wuu\",\"doi\":\"10.1109/JSEN.2025.3552595\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this study, we prepared various aluminum-doped zinc oxide (AZO) surface structures via chemical bath deposition (CBD) for use in biomedical sensors. Indium tin oxide (ITO) conductive films were deposited on glass substrates via electron beam evaporation, and AZO nanorods were subsequently grown on the ITO layer using CBD at a bath temperature of <inline-formula> <tex-math>$90~^{\\\\circ }$ </tex-math></inline-formula>C. The AZO/ITO sensor electrode was further optimized through furnace annealing, improving its structural and electrical properties. This nanostructure enhances the ability of biomedical sensor films to adsorb H+ and OH<inline-formula> <tex-math>${}^{-}$ </tex-math></inline-formula> ions by increasing the reactive surface area between the film and the solution under test, thereby improving pH sensitivity. In addition, we used an extended gate field effect transistor (EGFET) module to measure glucose concentrations ranging from 0 to 10 mg/ml, achieving sensitivity values of 55.4 mV/pH and 8.07 mA/mg<inline-formula> <tex-math>$\\\\cdot $ </tex-math></inline-formula>ml<inline-formula> <tex-math>${}^{-{1}}$ </tex-math></inline-formula>. These findings have significant implications for the future development of blood glucose monitoring and microenvironmental sensing systems.\",\"PeriodicalId\":447,\"journal\":{\"name\":\"IEEE Sensors Journal\",\"volume\":\"25 10\",\"pages\":\"16648-16657\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2025-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Sensors Journal\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://ieeexplore.ieee.org/document/10938172/\",\"RegionNum\":2,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Sensors Journal","FirstCategoryId":"103","ListUrlMain":"https://ieeexplore.ieee.org/document/10938172/","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
Fabrication and Characterization of Aluminum-Doped ZnO Nanorods for Biosensor Applications
In this study, we prepared various aluminum-doped zinc oxide (AZO) surface structures via chemical bath deposition (CBD) for use in biomedical sensors. Indium tin oxide (ITO) conductive films were deposited on glass substrates via electron beam evaporation, and AZO nanorods were subsequently grown on the ITO layer using CBD at a bath temperature of $90~^{\circ }$ C. The AZO/ITO sensor electrode was further optimized through furnace annealing, improving its structural and electrical properties. This nanostructure enhances the ability of biomedical sensor films to adsorb H+ and OH${}^{-}$ ions by increasing the reactive surface area between the film and the solution under test, thereby improving pH sensitivity. In addition, we used an extended gate field effect transistor (EGFET) module to measure glucose concentrations ranging from 0 to 10 mg/ml, achieving sensitivity values of 55.4 mV/pH and 8.07 mA/mg$\cdot $ ml${}^{-{1}}$ . These findings have significant implications for the future development of blood glucose monitoring and microenvironmental sensing systems.
期刊介绍:
The fields of interest of the IEEE Sensors Journal are the theory, design , fabrication, manufacturing and applications of devices for sensing and transducing physical, chemical and biological phenomena, with emphasis on the electronics and physics aspect of sensors and integrated sensors-actuators. IEEE Sensors Journal deals with the following:
-Sensor Phenomenology, Modelling, and Evaluation
-Sensor Materials, Processing, and Fabrication
-Chemical and Gas Sensors
-Microfluidics and Biosensors
-Optical Sensors
-Physical Sensors: Temperature, Mechanical, Magnetic, and others
-Acoustic and Ultrasonic Sensors
-Sensor Packaging
-Sensor Networks
-Sensor Applications
-Sensor Systems: Signals, Processing, and Interfaces
-Actuators and Sensor Power Systems
-Sensor Signal Processing for high precision and stability (amplification, filtering, linearization, modulation/demodulation) and under harsh conditions (EMC, radiation, humidity, temperature); energy consumption/harvesting
-Sensor Data Processing (soft computing with sensor data, e.g., pattern recognition, machine learning, evolutionary computation; sensor data fusion, processing of wave e.g., electromagnetic and acoustic; and non-wave, e.g., chemical, gravity, particle, thermal, radiative and non-radiative sensor data, detection, estimation and classification based on sensor data)
-Sensors in Industrial Practice