评估双能计算机断层扫描（DECT）衍生的椎间肌脂肪含量和计算机断层扫描（CT）衰减对腰椎间盘退变的诊断效果

IF 2.1 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical radiology Pub Date : 2025-03-04 DOI:10.1016/j.crad.2025.106864

Z. Meng , M. Liu , A. Xiong, Y. Guo, S. Deng, J. Cao, X. Tian, X. Meng, J. Qin, X. Wang

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引用次数: 0

摘要

目的评价双能ct （DECT）衍生多裂肌（MF）和竖脊肌（ES）脂肪含量对腰椎间盘退变的诊断价值。材料与方法一项回顾性研究分析了36例在一周内接受DECT和磁共振成像的患者，评估了不同年龄（青年、中年、老年）和性别群体（女性、男性）的Pfirrmann分级。绘制roi来测量脂肪分数（FF）和CT衰减（HU）。在总样本、年龄和性别组中检验MF-HU、MF-FF、ES-HU和ES-FF与Pfirrmann分级的相关性。HU、FF在年龄、性别组及Pfirrmann分级组间的差异有统计学意义。采用受试者工作特征曲线（AUC）分析，评价MF-FF、ES-FF以及体质指数(BMI) +年龄+ MF-FF/ES-FF联合模型的性能和临界值。结果smf - ff、ES-FF与Pfirrmann分级呈中度相关（r = 0.587、0.587）。青壮年组Pfirrmann评分高于中老年组（r = 0.579, 0.605），女性Pfirrmann评分高于男性（r = 0.614, 0.602）。各年龄组女性MF-FF和ES-FF均显著高于男性(P <；0.05)。≥2和≥3级时，MF-FF和ES-FF的AUC值高于其他指标。BMI +年龄+ MF-FF/ES-FF联合模型提高了≥4级和≥5级的AUC值，特别是≥5级。结论mf - ff和ES-FF在青年组表现出较强的相关性，在各年龄组中均优于男性。与晚期相比，早期椎间盘退变的诊断价值更高。BMI +年龄+ MF-FF/ES-FF联合模型弥补了晚期椎间盘退变的诊断局限性。

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Evaluation of the diagnostic efficacy of dual-energy computed tomography (DECT)-derived intervertebral muscle fat content and computed tomography (CT) attenuation for lumbar intervertebral disc degeneration

AIM

To evaluate the diagnostic performance of dual-energy computed tomography (DECT)-derived multifidus (MF) and erector spinae (ES) muscle fat content for lumbar intervertebral disc degeneration.

MATERIAL AND METHODS

A retrospective study analysed 36 patients who underwent DECT and magnetic resonance imaging within a week, assessing Pfirrmann grade across age (young, middle, elderly) and gender groups (female, male). ROIs were delineated to measure fat fraction (FF) and CT attenuation (HU). Correlation of MF-HU, MF-FF, ES-HU, and ES-FF with Pfirrmann grade was examined in total samples, age, and gender groups. Statistical differences in HU and FF among age and gender groups and Pfirrmann grade groups were compared. Receiver operating characteristic curve (AUC) analysis was performed to evaluate the performance and cutoff values of MF-FF, ES-FF, and combined models with body mass index (BMI) + age + MF-FF/ES-FF.

RESULTS

MF-FF、ES-FF showed moderate correlation with Pfirrmann grade (r = 0.587, 0.587). Values were higher in the young-age group (r = 0.579, 0.605) than in the middle-aged and high-year groups, with values in females (r = 0.614, 0.602) associated with higher Pfirrmann grade than in males. Female MF-FF and ES-FF were significantly higher than their male counterparts in each age group (P < 0.05). AUC values for MF-FF and ES-FF were higher than other indicators in grades ≥2 and ≥ 3. Combined models of BMI + age + MF-FF/ES-FF improved AUC values in grades ≥4 and ≥ 5, especially for grades ≥5.

CONCLUSION

MF-FF and ES-FF exhibit stronger correlations in the young-age group, surpassing males in all age groups. Their diagnostic value is higher in early lumbar intervertebral disc degeneration compared to later stages. The combined model of BMI + age + MF-FF/ES-FF compensates for the diagnostic limitations in advanced intervertebral disc degeneration.

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来源期刊

Clinical radiology 医学-核医学

CiteScore

4.70

自引率

3.80%

发文量

528

审稿时长

76 days

期刊介绍： Clinical Radiology is published by Elsevier on behalf of The Royal College of Radiologists. Clinical Radiology is an International Journal bringing you original research, editorials and review articles on all aspects of diagnostic imaging, including: • Computed tomography • Magnetic resonance imaging • Ultrasonography • Digital radiology • Interventional radiology • Radiography • Nuclear medicine Papers on radiological protection, quality assurance, audit in radiology and matters relating to radiological training and education are also included. In addition, each issue contains correspondence, book reviews and notices of forthcoming events.