探索细胞核：从染色体结构到单细胞组学

IF 4.3 2区生物学 Q1 CELL BIOLOGY

Current Opinion in Cell Biology Pub Date : 2025-05-16 DOI:10.1016/j.ceb.2025.102530

Tatsuo Fukagawa, Maria Elena Torres-Padilla

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引用次数: 0

摘要

细胞核是一个迷人的细胞器。确保遗传信息被正确读取和忠实传递的无数基本过程为跨时间尺度和模型系统的研究提供了丰富的主题。从染色体的“元尺度”组织和分裂（由着丝点等分子机制实现），到间期细胞分裂后的基因组组织（可实现基因调控的微调），这些主题都是我们在《细胞生物学最新观点》的“细胞核”问题中所涉及的主题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Exploring the cell nucleus: From chromosome structure to single-cell omics

The cell nucleus is a fascinating organelle. The myriad of fundamental processes that ensure that the genetic information is read correctly and faithfully transmitted provides a rich subject of research across time scales and model systems. Topics ranging from chromosome ‘metascale’ organization and division, enabled by molecular machineries like the kinetochore, to the organization of the genome that ensues cell division during interphase, which enables fine tuning of gene regulation, are subjects that we cover in the ‘Cell Nucleus’ issue of Current Opinion in Cell Biology.

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来源期刊

Current Opinion in Cell Biology 生物-细胞生物学

CiteScore

14.60

自引率

1.30%

发文量

审稿时长

93 days

期刊介绍： Current Opinion in Cell Biology (COCEBI) is a highly respected journal that specializes in publishing authoritative, comprehensive, and systematic reviews in the field of cell biology. The journal's primary aim is to provide a clear and readable synthesis of the latest advances in cell biology, helping specialists stay current with the rapidly evolving field. Expert authors contribute to the journal by annotating and highlighting the most significant papers from the extensive body of research published annually, offering valuable insights and saving time for readers by distilling key findings. COCEBI is part of the Current Opinion and Research (CO+RE) suite of journals, which leverages the legacy of editorial excellence, high impact, and global reach to ensure that the journal is a widely read resource integral to scientists' workflow. It is published by Elsevier, a publisher known for its commitment to excellence in scientific publishing and the communication of reproducible biomedical research aimed at improving human health. The journal's content is designed to be an invaluable resource for a diverse audience, including researchers, lecturers, teachers, professionals, policymakers, and students.