全球视野下慢性伤口的知识结构与研究热点

IF 3.4 3区环境科学与生态学 Q3 CELL & TISSUE ENGINEERING

Regenerative Therapy Pub Date : 2025-05-17 DOI:10.1016/j.reth.2025.05.002

Yushu Zhu , Yizhen Lin , Sujie Xie , Mingxuan Yang , Wei Zhang , Minjuan Wu , Yifan Liu , Dayuan Xu , Shuyuan Xian , Xirui Tong , Jie Huang , Luofeng Jiang , Xinya Guo , Minyi Gu , Hengkai Yu , Xinran Ding , Yixu Li , Yiyao Du , Heng He , Jianyu Lu , Shizhao Ji

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引用次数: 0

摘要

慢性伤口包括但不限于糖尿病足溃疡、下肢静脉溃疡和压疮。难以治愈的挑战给患者和社会带来了沉重的负担。我们的目的是解释慢性伤口的愈合过程和治疗技术在过去几年的发展，并提供相关的，有价值的信息。方法从Web of Science （WoSCC）数据库的核心馆藏中检索5篇科学出版物。采用基于R-bibliometrix的Biblioshiny软件进行文献计量可视化分析。由VOSviewer软件和Citespace软件对结果进行验证。结果共检索到与慢性创面愈合相关的文献8129篇。发表数量最多的国家、机构和期刊分别是美国、N8研究伙伴关系和《伤口护理杂志》。Armstrong DG和Dumville JC是该领域最具影响力的作者。关键词分析显示了“敷料”和“管理”两个关键集群。趋势话题分析揭示了近年来频繁出现的关键词，包括“纳米纤维”和“可注射水凝胶”。结论我们的研究首次通过计量学和系统评价揭示了未来慢性伤口愈合过程中的细胞分子机制和关键的临床管理策略，在未来可能具有重要的转化价值。

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Mapping intellectual structures and research hotspots of chronic wound in global perspective

Background

Chronic wounds included but were not limited to diabetes foot ulcers, venous leg ulcers and pressure ulcers. The challenge of difficult healing placed a heavy burden on patients and society. Our objective was to explain the healing process of chronic wounds and the development of treatment technologies in the past few years and to provide relevant, valuable information.

Methods

Our scientific publications were retrieved from the core collection of the Web of Science (WoSCC) database collection. The bibliometric visualization and analysis were performed by the software Biblioshiny based on R-bibliometrix. VOSviewer software and Citespace software were responsible for the validation of the results.

Results

A total of 8129 articles related to wound healing in chronic wounds were retrieved. The countries, institutions, and journals with the highest number of publications were the USA, the N8 research partnership, and the Journal of Wound Care, respectively. Armstrong DG and Dumville JC were the most influential authors in this field. The keyword analysis showed two key clusters of keywords, including “dressings” and “management”. Trend topics analysis revealed frequent keywords in recent years, including “nanofibers” and “injectable hydrogels”.

Conclusion

Our research was the first to reveal the cellular and molecular mechanisms and key clinical management strategies in the healing process of chronic wounds in the future through metrological and systematic evaluation, which may have important translational value in the future.

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来源期刊

Regenerative Therapy Engineering-Biomedical Engineering

CiteScore

6.00

自引率

2.30%

发文量

106

审稿时长

49 days

期刊介绍： Regenerative Therapy is the official peer-reviewed online journal of the Japanese Society for Regenerative Medicine. Regenerative Therapy is a multidisciplinary journal that publishes original articles and reviews of basic research, clinical translation, industrial development, and regulatory issues focusing on stem cell biology, tissue engineering, and regenerative medicine.