Idowu O. Malachi , Adebukola O. Olawumi , B.I. Oladapo
{"title":"使用参数化建模的人工智能驱动的脊柱植入物设计优化","authors":"Idowu O. Malachi , Adebukola O. Olawumi , B.I. Oladapo","doi":"10.1016/j.colsurfb.2025.114753","DOIUrl":null,"url":null,"abstract":"<div><div>This study aimed to enhance vertebral implant design by using a parametric spine model and advanced simulation techniques to evaluate biomechanical behaviours under dynamic physiological conditions using Finite Element Analysis (FEA) in ANSYS Workbench. The primary objective was to refine implant designs to improve surgical outcomes and patient safety. We incorporated the anisotropic material properties of Magnesium-Rare Earth-Zirconium (Mg-RE-Zr) alloys, focusing on their Young's modulus (40–50 GPa), Poisson's ratio (0.35), and yield strengths (0.193 GPa tensile, 0.255 GPa compressive) to simulate real-world stress and deformation scenarios. Using Finite Element Analysis (FEA), we conducted a series of simulations to examine stress distribution and deformation patterns across various implant models under static and dynamic loads. These simulations provided detailed insights, revealing that maximum equivalent stresses could reach up to 0.160 GPa, with deformations ranging from 0.01875 mm at a lower modulus to 0.015 mm at a higher modulus, showcasing the influence of material stiffness on implant performance. The model demonstrated high accuracy, with an error margin of less than 5 % when validated against analysis test data. This research makes a significant contribution to the field by providing a validated method for predicting and enhancing the biomechanical performance of spinal implants, thereby ensuring their reliability and efficacy in clinical applications.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"253 ","pages":"Article 114753"},"PeriodicalIF":5.4000,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"AI-driven optimization of spinal implant design using parametric modelling\",\"authors\":\"Idowu O. Malachi , Adebukola O. Olawumi , B.I. Oladapo\",\"doi\":\"10.1016/j.colsurfb.2025.114753\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>This study aimed to enhance vertebral implant design by using a parametric spine model and advanced simulation techniques to evaluate biomechanical behaviours under dynamic physiological conditions using Finite Element Analysis (FEA) in ANSYS Workbench. The primary objective was to refine implant designs to improve surgical outcomes and patient safety. We incorporated the anisotropic material properties of Magnesium-Rare Earth-Zirconium (Mg-RE-Zr) alloys, focusing on their Young's modulus (40–50 GPa), Poisson's ratio (0.35), and yield strengths (0.193 GPa tensile, 0.255 GPa compressive) to simulate real-world stress and deformation scenarios. Using Finite Element Analysis (FEA), we conducted a series of simulations to examine stress distribution and deformation patterns across various implant models under static and dynamic loads. These simulations provided detailed insights, revealing that maximum equivalent stresses could reach up to 0.160 GPa, with deformations ranging from 0.01875 mm at a lower modulus to 0.015 mm at a higher modulus, showcasing the influence of material stiffness on implant performance. The model demonstrated high accuracy, with an error margin of less than 5 % when validated against analysis test data. This research makes a significant contribution to the field by providing a validated method for predicting and enhancing the biomechanical performance of spinal implants, thereby ensuring their reliability and efficacy in clinical applications.</div></div>\",\"PeriodicalId\":279,\"journal\":{\"name\":\"Colloids and Surfaces B: Biointerfaces\",\"volume\":\"253 \",\"pages\":\"Article 114753\"},\"PeriodicalIF\":5.4000,\"publicationDate\":\"2025-05-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Colloids and Surfaces B: Biointerfaces\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0927776525002607\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Colloids and Surfaces B: Biointerfaces","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0927776525002607","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOPHYSICS","Score":null,"Total":0}
AI-driven optimization of spinal implant design using parametric modelling
This study aimed to enhance vertebral implant design by using a parametric spine model and advanced simulation techniques to evaluate biomechanical behaviours under dynamic physiological conditions using Finite Element Analysis (FEA) in ANSYS Workbench. The primary objective was to refine implant designs to improve surgical outcomes and patient safety. We incorporated the anisotropic material properties of Magnesium-Rare Earth-Zirconium (Mg-RE-Zr) alloys, focusing on their Young's modulus (40–50 GPa), Poisson's ratio (0.35), and yield strengths (0.193 GPa tensile, 0.255 GPa compressive) to simulate real-world stress and deformation scenarios. Using Finite Element Analysis (FEA), we conducted a series of simulations to examine stress distribution and deformation patterns across various implant models under static and dynamic loads. These simulations provided detailed insights, revealing that maximum equivalent stresses could reach up to 0.160 GPa, with deformations ranging from 0.01875 mm at a lower modulus to 0.015 mm at a higher modulus, showcasing the influence of material stiffness on implant performance. The model demonstrated high accuracy, with an error margin of less than 5 % when validated against analysis test data. This research makes a significant contribution to the field by providing a validated method for predicting and enhancing the biomechanical performance of spinal implants, thereby ensuring their reliability and efficacy in clinical applications.
期刊介绍:
Colloids and Surfaces B: Biointerfaces is an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, having particular relevance to the medical, pharmaceutical, biotechnological, food and cosmetic fields.
Submissions that: (1) deal solely with biological phenomena and do not describe the physico-chemical or colloid-chemical background and/or mechanism of the phenomena, and (2) deal solely with colloid/interfacial phenomena and do not have appropriate biological content or relevance, are outside the scope of the journal and will not be considered for publication.
The journal publishes regular research papers, reviews, short communications and invited perspective articles, called BioInterface Perspectives. The BioInterface Perspective provide researchers the opportunity to review their own work, as well as provide insight into the work of others that inspired and influenced the author. Regular articles should have a maximum total length of 6,000 words. In addition, a (combined) maximum of 8 normal-sized figures and/or tables is allowed (so for instance 3 tables and 5 figures). For multiple-panel figures each set of two panels equates to one figure. Short communications should not exceed half of the above. It is required to give on the article cover page a short statistical summary of the article listing the total number of words and tables/figures.