利用纳米材料中的光能转换进行精密治疗。

IF 27.4 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Materials Pub Date : 2025-05-16 DOI:10.1002/adma.202501623

Jingyu Shi,Yadi Fan,Qin Zhang,Yingying Huang,Mo Yang

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引用次数: 0

摘要

快速发展的治疗学领域旨在将治疗和诊断功能整合到精准医学的单一平台中，从而实现疾病的同时治疗和监测。基于光能转换的纳米材料已经成为一个多功能的平台，它利用光的独特特性来激活具有高空间和时间精度的治疗。本文综述了利用纳米材料进行光能转换的最新进展，重点介绍了纳米材料在疾病治疗中的应用。讨论首先探讨了纳米材料中光能转换的基本原理，包括所使用的材料类型和各种光触发机制，如光致发光、光热、光电、光声、光触发SERS和光动力过程。随后，本文深入探讨了光能转换在纳米材料中的广泛应用，强调了它们在主要疾病的诊断和治疗中的作用，包括癌症、神经退行性疾病、视网膜变性和骨关节炎。最后，讨论了基于光能转换的精准治疗技术面临的挑战和机遇，旨在推进个性化医疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Harnessing Photo-Energy Conversion in Nanomaterials for Precision Theranostics.

The rapidly advancing field of theranostics aims to integrate therapeutic and diagnostic functionalities into a single platform for precision medicine, enabling the simultaneous treatment and monitoring of diseases. Photo-energy conversion-based nanomaterials have emerged as a versatile platform that utilizes the unique properties of light to activate theranostics with high spatial and temporal precision. This review provides a comprehensive overview of recent developments in photo-energy conversion using nanomaterials, highlighting their applications in disease theranostics. The discussion begins by exploring the fundamental principles of photo-energy conversion in nanomaterials, including the types of materials used and various light-triggered mechanisms, such as photoluminescence, photothermal, photoelectric, photoacoustic, photo-triggered SERS, and photodynamic processes. Following this, the review delves into the broad spectrum of applications of photo-energy conversion in nanomaterials, emphasizing their role in the diagnosis and treatment of major diseases, including cancer, neurodegenerative disorders, retinal degeneration, and osteoarthritis. Finally, the challenges and opportunities of photo-energy conversion-based technologies for precision theranostics are discussed, aiming to advance personalized medicine.

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来源期刊

Advanced Materials 工程技术-材料科学：综合

CiteScore

43.00

自引率

4.10%

发文量

2182

审稿时长

2 months

期刊介绍： Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.