{"title":"CNN-GRU高光谱成像对胃腺瘤性息肉及腺癌分类的分析。","authors":"Xuzhe Wang, Xiaoqing Yue, Tianyi Hang, Shuai Liu","doi":"10.1002/jbio.70047","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Early identification of gastric adenomatous polyps and adenocarcinoma is vital for improving patient outcomes. This study proposes a hybrid CNN-GRU model to classify one-dimensional hyperspectral data from ex vivo gastric tissues, addressing limitations of traditional diagnostics. Our model innovatively combines convolutional neural networks (CNNs) and gated recurrent units (GRUs) to capture both spatial and sequential dependencies in spectral data. Experimental results demonstrate that our model achieves an accuracy of 86%, sensitivity of 88%, and specificity of 85%. Additionally, receiver operating characteristic analysis further underscores its robust performance with an area under the curve of 0.86, surpassing traditional methods and other baseline models. These findings highlight the potential of leveraging advanced machine learning techniques to enhance early diagnostic accuracy and treatment strategies. The proposed approach offers a promising tool for rapid, accurate differentiation of gastric lesions, underscoring the importance of integrating innovative technologies in clinical diagnostics.</p>\n </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"18 9","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of Hyperspectral Imaging Using CNN-GRU for Gastric Adenomatous Polyp and Adenocarcinoma Classification\",\"authors\":\"Xuzhe Wang, Xiaoqing Yue, Tianyi Hang, Shuai Liu\",\"doi\":\"10.1002/jbio.70047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>Early identification of gastric adenomatous polyps and adenocarcinoma is vital for improving patient outcomes. This study proposes a hybrid CNN-GRU model to classify one-dimensional hyperspectral data from ex vivo gastric tissues, addressing limitations of traditional diagnostics. Our model innovatively combines convolutional neural networks (CNNs) and gated recurrent units (GRUs) to capture both spatial and sequential dependencies in spectral data. Experimental results demonstrate that our model achieves an accuracy of 86%, sensitivity of 88%, and specificity of 85%. Additionally, receiver operating characteristic analysis further underscores its robust performance with an area under the curve of 0.86, surpassing traditional methods and other baseline models. These findings highlight the potential of leveraging advanced machine learning techniques to enhance early diagnostic accuracy and treatment strategies. The proposed approach offers a promising tool for rapid, accurate differentiation of gastric lesions, underscoring the importance of integrating innovative technologies in clinical diagnostics.</p>\\n </div>\",\"PeriodicalId\":184,\"journal\":{\"name\":\"Journal of Biophotonics\",\"volume\":\"18 9\",\"pages\":\"\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-04-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biophotonics\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jbio.70047\",\"RegionNum\":3,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biophotonics","FirstCategoryId":"101","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jbio.70047","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Analysis of Hyperspectral Imaging Using CNN-GRU for Gastric Adenomatous Polyp and Adenocarcinoma Classification
Early identification of gastric adenomatous polyps and adenocarcinoma is vital for improving patient outcomes. This study proposes a hybrid CNN-GRU model to classify one-dimensional hyperspectral data from ex vivo gastric tissues, addressing limitations of traditional diagnostics. Our model innovatively combines convolutional neural networks (CNNs) and gated recurrent units (GRUs) to capture both spatial and sequential dependencies in spectral data. Experimental results demonstrate that our model achieves an accuracy of 86%, sensitivity of 88%, and specificity of 85%. Additionally, receiver operating characteristic analysis further underscores its robust performance with an area under the curve of 0.86, surpassing traditional methods and other baseline models. These findings highlight the potential of leveraging advanced machine learning techniques to enhance early diagnostic accuracy and treatment strategies. The proposed approach offers a promising tool for rapid, accurate differentiation of gastric lesions, underscoring the importance of integrating innovative technologies in clinical diagnostics.
期刊介绍:
The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.