Ruiyong Yang, Meiting Liu, Chenglin Tang, Shanshan Wang
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The quality of the included studies was assessed using the Cochrane Collaboration's tool for assessing the risk of bias, and the data were analyzed using Revman5.4, StataMP 18, and TSA0.9.5.10Beta software.</p><p><strong>Results: </strong>A total of 7 randomized controlled trials involving 714 patients were included. The meta-analysis results showed that acupuncture combined with Western medication was superior to simple Western medication in improving the blood flow velocity of the left vertebral artery, right vertebral artery, and basilar artery in patients with CV, improving the symptoms of cervical vertigo and improving its function and clinical efficacy. TSA analysis results again confirmed the robustness of the results of this meta-analysis.</p><p><strong>Conclusion: </strong>Acupuncture combined with Western medicine has measurable benefits in improving vertebrobasilar hemodynamics and clinical efficacy in patients with CV, with certain safety. However, there are still methodological defects such as small sample size, different acupuncture treatment methods, and information on minimal clinically relevant differences is missing. 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引用次数: 0
摘要
目的：系统评价针刺结合西药对颈性眩晕患者椎基底动脉血流动力学的影响及其临床疗效。为临床治疗CV提供可靠的循证医学依据。方法：本系统评价和荟萃分析报告将与meta分析（PRISMA2020）声明一致。截止到2024年8月20日，检索了MEDLINE、Embase、Web of Science、Cochrane Library、CNKI、VIP、万方、China Biology Medicine Disc （CBM）。采用Cochrane Collaboration的偏倚风险评估工具对纳入研究的质量进行评估，并使用Revman5.4、StataMP 18和TSA0.9.5.10Beta软件对数据进行分析。结果：共纳入7项随机对照试验，714例患者。meta分析结果显示，针刺联合西药在改善CV患者左椎动脉、右椎动脉、基底动脉血流速度、改善颈性眩晕症状、改善其功能及临床疗效方面优于单纯西药。TSA分析结果再次证实了该meta分析结果的稳健性。结论：针刺结合西药对改善CV患者椎基底血流动力学和临床疗效有明显的益处，且具有一定的安全性。然而，仍然存在方法学上的缺陷，如样本量小，针灸治疗方法不同，以及缺乏有关最小临床相关差异的信息。未来还需要更大样本量、更长观察时间的随机对照试验来进一步验证针灸与西药联合治疗CV的疗效，并可进行更新的meta分析来分析针灸与西药联合治疗CV的疗效。系统评价注册：PROSPERO CRD42024592131。
Effect of acupuncture combined with Western medicine on vertebrobasilar artery hemodynamics and efficacy in patients with CV: a systematic review and meta-analysis.
Objective: To systematically evaluate the effect of acupuncture combined with Western medicine on vertebrobasilar artery hemodynamics and its clinical efficacy in patients with cervical vertigo. To provide a reliable evidence-based medical basis for the clinical treatment of CV.
Methods: This systematic review and meta-analysis will be reported in agreement with the Meta-Analyses (PRISMA2020) statement. MEDLINE, Embase, Web of Science, the Cochrane Library, CNKI, VIP, Wan Fang, and China Biology Medicine Disc (CBM) were searched until August 20, 2024. The quality of the included studies was assessed using the Cochrane Collaboration's tool for assessing the risk of bias, and the data were analyzed using Revman5.4, StataMP 18, and TSA0.9.5.10Beta software.
Results: A total of 7 randomized controlled trials involving 714 patients were included. The meta-analysis results showed that acupuncture combined with Western medication was superior to simple Western medication in improving the blood flow velocity of the left vertebral artery, right vertebral artery, and basilar artery in patients with CV, improving the symptoms of cervical vertigo and improving its function and clinical efficacy. TSA analysis results again confirmed the robustness of the results of this meta-analysis.
Conclusion: Acupuncture combined with Western medicine has measurable benefits in improving vertebrobasilar hemodynamics and clinical efficacy in patients with CV, with certain safety. However, there are still methodological defects such as small sample size, different acupuncture treatment methods, and information on minimal clinically relevant differences is missing. In the future, RCTs with larger sample sizes and longer observations are still needed to further verify the efficacy of acupuncture combined with Western medicine, and an updated meta-analysis can be conducted to analyze the efficacy of acupuncture combined with Western medicine in the treatment of CV.
期刊介绍：
Systematic Reviews encompasses all aspects of the design, conduct and reporting of systematic reviews. The journal publishes high quality systematic review products including systematic review protocols, systematic reviews related to a very broad definition of health, rapid reviews, updates of already completed systematic reviews, and methods research related to the science of systematic reviews, such as decision modelling. At this time Systematic Reviews does not accept reviews of in vitro studies. The journal also aims to ensure that the results of all well-conducted systematic reviews are published, regardless of their outcome.
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